64917-82-4

64917-82-4 structure

Name: Schisantherin D
Chemical Name: schisantherin D
CAS Number: 64917-82-4
Molecular Formula: C₂₉H₂₈O₉
Molecular Weight: 520.52700
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2018-02-06 00:39:27
Modify Date: 2024-01-02 09:08:53
Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects[1][2].

Name	schisantherin D
Synonyms	schizantherin D

Description	Schisantherin D is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin D shows anti-HIV replication activities with an EC50 of 0.5 μg/mL. Schisantherin D inhibits endothelin receptor B (ETBR) and has hepatoprotective effects[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	EC50: 0.5 μg/mL (HIV)[1]
References	[1]. D F Chen, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8. [2]. Jin-Biao Xu, et al. Lignans from Schisandra chinensis ameliorate alcohol and CCl 4-induced long-term liver injury and reduce hepatocellular degeneration via blocking ETBR. J Ethnopharmacol. 2020 Aug 10;258:112813.

Hazard Codes	Xi