Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)

Modify Date: 2025-08-25 00:31:38

Bouvardin,5-(N-methyl-L-tyrosine)- (9CI) structure	Common Name	Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)
	CAS Number	64725-24-2	Molecular Weight	756.84400
	Density	1.189g/cm3	Boiling Point	1083.3ºC at 760mmHg
	Molecular Formula	C₄₀H₄₈N₆O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	609ºC

Use of Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)

RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.

Name	deoxyBouvardin
Synonym	More Synonyms

Description	RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt Signaling Pathways >> Stem Cell/Wnt >> Notch Signaling Pathways >> Apoptosis >> c-Myc
Target	IC50: 50 ng/mL (Wnt); 75 ng/mL (Myc), 93 ng/mL (Notch)[1]
In Vivo	RA-V 对 Wnt、Myc 和 Notch 具有活性，IC50 值分别为 50、75 和 93 ng/mL[1]。
References	[1]. Premalatha Balachandran, et al. Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia. Molecules. 2021 Jan 31;26(3):735.

Density	1.189g/cm3
Boiling Point	1083.3ºC at 760mmHg
Molecular Formula	C₄₀H₄₈N₆O₉
Molecular Weight	756.84400
Flash Point	609ºC
Exact Mass	756.34800
PSA	186.92000
LogP	2.34320
Index of Refraction	1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ED9610000

CAS REGISTRY NUMBER :: 64725-24-2

LAST UPDATED :: 198702

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C40-H48-N6-O9.5/4H2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984

Precursor 8
CAS#:122621-60-7 cyclo(D-alanyl-... CAS#:135226-85-6 N,O4-dimethyl-L... CAS#:110774-03-3 3-Acetyl-N-benz... CAS#:135226-84-5 3-hydroxy-N,O-d...
CAS#:135226-82-3 3-acetyl-N,O-di... CAS#:135226-87-8 4-iodo-N-methyl... CAS#:135226-89-0 methyl 4-methox... CAS#:109011-08-7 L,L-N,N-dimethy...
DownStream 4
CAS#:86157-27-9 6-(O-Hexyl-3-hy... CAS#:86229-74-5 5-(N-Methyl-L-t... CAS#:86229-75-6 Acetyl ester of... CAS#:86229-85-8 5-(N-Methyl-L-t...

Desoxybenzoin-semicarbazon

1,2-diphenyl-ethanone semicarbazone

Semicarbazon des Phenyl-benzyl-ketons

deoxybouvadin

Benzyl-phenyl-keton-semicarbazon

1,2-Diphenyl-1-semicarbazonoethan

deoxybenzoin semicarbazone

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Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)
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Purity: 98.0%
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