Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)
Names
[ CAS No. ]:
64725-24-2
[ Name ]:
Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)
[Synonym ]:
Desoxybenzoin-semicarbazon
1,2-diphenyl-ethanone semicarbazone
Semicarbazon des Phenyl-benzyl-ketons
deoxybouvadin
Benzyl-phenyl-keton-semicarbazon
1,2-Diphenyl-1-semicarbazonoethan
deoxybenzoin semicarbazone
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 50 ng/mL (Wnt); 75 ng/mL (Myc), 93 ng/mL (Notch)[1]
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
1.189g/cm3
[ Boiling Point ]:
1083.3ºC at 760mmHg
[ Molecular Formula ]:
C40H48N6O9
[ Molecular Weight ]:
756.84400
[ Flash Point ]:
609ºC
[ Exact Mass ]:
756.34800
[ PSA ]:
186.92000
[ LogP ]:
2.34320
[ Index of Refraction ]:
1.544
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ED9610000
- CAS REGISTRY NUMBER :
- 64725-24-2
- LAST UPDATED :
- 198702
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C40-H48-N6-O9.5/4H2-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 16 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 34 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984