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64725-24-2

64725-24-2 structure
64725-24-2 structure
  • Name: Bouvardin,5-(N-methyl-L-tyrosine)- (9CI)
  • Chemical Name: deoxyBouvardin
  • CAS Number: 64725-24-2
  • Molecular Formula: C40H48N6O9
  • Molecular Weight: 756.84400
  • Catalog: Signaling Pathways Apoptosis c-Myc
  • Create Date: 2017-02-21 09:10:37
  • Modify Date: 2025-08-25 00:31:38
  • RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.
Name deoxyBouvardin
Synonyms Desoxybenzoin-semicarbazon
1,2-diphenyl-ethanone semicarbazone
Semicarbazon des Phenyl-benzyl-ketons
deoxybouvadin
Benzyl-phenyl-keton-semicarbazon
1,2-Diphenyl-1-semicarbazonoethan
deoxybenzoin semicarbazone
Description RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.
Related Catalog
Target

IC50: 50 ng/mL (Wnt); 75 ng/mL (Myc), 93 ng/mL (Notch)[1]

In Vivo RA-V 对 Wnt、Myc 和 Notch 具有活性，IC50 值分别为 50、75 和 93 ng/mL[1]。
References

[1]. Premalatha Balachandran, et al. Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia. Molecules. 2021 Jan 31;26(3):735.  

Density 1.189g/cm3
Boiling Point 1083.3ºC at 760mmHg
Molecular Formula C40H48N6O9
Molecular Weight 756.84400
Flash Point 609ºC
Exact Mass 756.34800
PSA 186.92000
LogP 2.34320
Index of Refraction 1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ED9610000
CAS REGISTRY NUMBER :
64725-24-2
LAST UPDATED :
198702
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C40-H48-N6-O9.5/4H2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
34 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,3216,1984
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