Bemegride structure
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Common Name | Bemegride | ||
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CAS Number | 64-65-3 | Molecular Weight | 155.194 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 282.0±9.0 °C at 760 mmHg | |
Molecular Formula | C8H13NO2 | Melting Point | 126-127 °C(lit.) | |
MSDS | N/A | Flash Point | 125.8±18.9 °C |
Use of BemegrideBemegride is a central nervous system stimulant and antidote for barbiturate poisoning.target: GABAA receptor Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. [1] Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression. [2] |
Name | 4-ethyl-4-methylpiperidine-2,6-dione |
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Synonym | More Synonyms |
Description | Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.target: GABAA receptor Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. [1] Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression. [2] |
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Related Catalog | |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 282.0±9.0 °C at 760 mmHg |
Melting Point | 126-127 °C(lit.) |
Molecular Formula | C8H13NO2 |
Molecular Weight | 155.194 |
Flash Point | 125.8±18.9 °C |
Exact Mass | 155.094635 |
PSA | 46.17000 |
LogP | 1.52 |
Appearance of Characters | powder | white |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.449 |
Storage condition | −20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Hazard Codes | T |
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Risk Phrases | R23/24/25 |
Safety Phrases | S22-S36/37/39-S45 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | MA4550000 |
Packaging Group | II |
Hazard Class | 6.1(a) |
HS Code | 2925190090 |
~% Bemegride CAS#:64-65-3 |
Literature: Collection of Czechoslovak Chemical Communications, , vol. 20, p. 1227,1232 |
~% Bemegride CAS#:64-65-3 |
Literature: Journal of the American Pharmaceutical Association (1912-1977), , vol. 39, p. 451,453 |
~% Bemegride CAS#:64-65-3 |
Literature: Journal of the American Pharmaceutical Association (1912-1977), , vol. 39, p. 451,453 Farmacja Polska, , vol. 15, p. 33 |
~% Bemegride CAS#:64-65-3 |
Literature: Yakugaku Zasshi, , vol. 77, p. 118 Chem.Abstr., , p. 8748 |
~% Bemegride CAS#:64-65-3 |
Literature: Journal of the Chemical Society, , vol. 99, p. 440 |
HS Code | 2925190090 |
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Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
3-ethyl-3-methylglutarimide |
EINECS 200-588-0 |
4-Ethyl-4-methyl-2,6-piperidinedione |
Bemegrid |
Ahypnon |
4-ethyl-4-methylglutarimide |
4-Ethyl-4-methylpiperidine-2,6-dione |
Antibarbi |
3-ethyl-3-methylgluarimide |
Methetharimide |
bemegride |
2,6-Piperidinedione, 4-ethyl-4-methyl- |
4-ethyl-4-methyl-piperidine-2,6-dione |
MFCD00006673 |
Zentraleptin |
Agipnon |
b,b-Methylethylglutarimide |
Megimide |