Acetoacetic acid sodium salt

Modify Date: 2024-01-03 23:13:56

Acetoacetic acid sodium salt Structure
Acetoacetic acid sodium salt structure
Common Name Acetoacetic acid sodium salt
CAS Number 623-58-5 Molecular Weight 124.07
Density N/A Boiling Point 237.7ºC at 760 mmHg
Molecular Formula C4H5NaO3 Melting Point N/A
MSDS N/A Flash Point 111.8ºC

 Use of Acetoacetic acid sodium salt


Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].

 Names

Name sodium,3-oxobutanoate
Synonym More Synonyms

 Acetoacetic acid sodium salt Biological Activity

Description Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1].
Related Catalog
In Vitro Acetoacetic acid sodium salt induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes[1]. Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes[1].
References

[1]. Shi X, et al. Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. J Dairy Res. 2016 Nov;83(4):442-446.

 Chemical & Physical Properties

Boiling Point 237.7ºC at 760 mmHg
Molecular Formula C4H5NaO3
Molecular Weight 124.07
Flash Point 111.8ºC
Exact Mass 124.01400
PSA 57.20000

 Safety Information

HS Code 2918300090

 Synthetic Route

~0%

Detail
Literature: Nippon Soda Co., Ltd. Patent: US5484949 A1, 1996 ;

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Acetoacetic acid sodium salt Structure

Acetoacetic aci...

CAS#:623-58-5

Literature: BASF Aktiengesellschaft Patent: US5428174 A1, 1995 ;

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Acetoacetic acid sodium salt Structure

Acetoacetic aci...

CAS#:623-58-5

Literature: Tommasi, Immacolata; Sorrentino, Fabiana Tetrahedron Letters, 2009 , vol. 50, # 1 p. 104 - 107

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Acetoacetic acid sodium salt Structure

Acetoacetic aci...

CAS#:623-58-5

Literature: Goemez-Bombarelli, Rafael; Gonzalez-Perez, Marina; Perez-Prior, Maria Teresa; Manso, Jose A.; Calle, Emilio; Casado, Julio Journal of Physical Organic Chemistry, 2009 , vol. 22, # 5 p. 438 - 442

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Acetoacetic acid sodium salt Structure

Acetoacetic aci...

CAS#:623-58-5

Literature: Franklin, M. C.; Short, W. F. Journal of the Chemical Society, 1928 , p. 591 - 595

 Customs

HS Code 2918300090
Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

Butanoic acid,3-oxo-,sodium salt
sodium acetoacetic acid ester
sodium acetoxyacetate
sodium 3-oxobutanoate
sodium acetylacetonate
acetoacetic acid,monosodium salt
Sodium Acetoacetate
Acetylacetic Acid Sodium salt
Acetoacetic acid sodium salt
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Price: ¥1320/10 mM * 1 mL in DMSO

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