(S)-3-Hydroxybutanoic acid

Modify Date: 2025-08-22 16:51:41

(S)-3-Hydroxybutanoic acid structure	Common Name	(S)-3-Hydroxybutanoic acid
	CAS Number	6168-83-8	Molecular Weight	104.10500
	Density	1.195 g/cm3	Boiling Point	269.2ºC at 760 mmHg
	Molecular Formula	C₄H₈O₃	Melting Point	45-48ºC
	MSDS	Chinese USA	Flash Point	121ºC
	Symbol	GHS07	Signal Word	Warning

Use of (S)-3-Hydroxybutanoic acid

(S)-3-Hydroxybutanoic acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.

Name	(S)-3-hydroxybutyric acid
Synonym	More Synonyms

Description	(S)-3-Hydroxybutanoic acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Others
Target	Human Endogenous Metabolite

Density	1.195 g/cm3
Boiling Point	269.2ºC at 760 mmHg
Melting Point	45-48ºC
Molecular Formula	C₄H₈O₃
Molecular Weight	104.10500
Flash Point	121ºC
Exact Mass	104.04700
PSA	57.53000
Index of Refraction	1.455
Storage condition	2-8°C

(S)-3-Hydroxybutanoic acid MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3

Precursor 8
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DownStream 4
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Thermophilic Coenzyme B12-Dependent Acyl Coenzyme A (CoA) Mutase from Kyrpidia tusciae DSM 2912 Preferentially Catalyzes Isomerization of (R)-3-Hydroxybutyryl-CoA and 2-Hydroxyisobutyryl-CoA.

Appl. Environ. Microbiol. 81 , 4564-72, (2015)

The recent discovery of a coenzyme B12-dependent acyl-coenzyme A (acyl-CoA) mutase isomerizing 3-hydroxybutyryl- and 2-hydroxyisobutyryl-CoA in the mesophilic bacterium Aquincola tertiaricarbonis L108...

Human brain beta-hydroxybutyrate and lactate increase in fasting-induced ketosis.

J. Cereb. Blood Flow Metab. 20(10) , 1502-7, (2000)

Ketones are known to constitute an important fraction of fuel for consumption by the brain, with brain ketone content generally thought to be low. However, the recent observation of 1-mmol/L levels of...

Contribution of 3-hydroxyisobutyrate to the measurement of 3-hydroxybutyrate in human plasma: comparison of enzymatic and gas-liquid chromatography-mass spectrometry assays in normal and in diabetic subjects.

J. Lipid Res. 30(11) , 1811-7, (1989)

In this study we employed a capillary gas-liquid chromatographic-mass spectrometric (GLC-MS) method to measure the plasma concentrations of 3-hydroxybutyrate (3-OHB) and 3-hydroxyisobutyrate (3-OHIB) ...

(3S)-3-hydroxybutanoic acid

(S)-3-Hydroxybutanoic acid