4-Methylumbelliferyl β-D-galactoside

Modify Date: 2024-01-02 12:51:57

4-Methylumbelliferyl β-D-galactoside Structure
4-Methylumbelliferyl β-D-galactoside structure
Common Name 4-Methylumbelliferyl β-D-galactoside
CAS Number 6160-78-7 Molecular Weight 338.309
Density 1.5±0.1 g/cm3 Boiling Point 626.9±55.0 °C at 760 mmHg
Molecular Formula C16H18O8 Melting Point 258-263ºC (dec.)
MSDS USA Flash Point 233.9±25.0 °C

 Use of 4-Methylumbelliferyl β-D-galactoside


4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer[1].

 Names

Name 4-Methylumbelliferyl-beta-D-galactopyranoside
Synonym More Synonyms

 4-Methylumbelliferyl β-D-galactoside Biological Activity

Description 4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer[1].
Related Catalog
References

[1]. Berg JD, et al. Rapid detection of total and fecal coliforms in water by enzymatic hydrolysis of 4-methylumbelliferone-beta-D-galactoside. Appl Environ Microbiol. 1988 Aug;54(8):2118-22.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 626.9±55.0 °C at 760 mmHg
Melting Point 258-263ºC (dec.)
Molecular Formula C16H18O8
Molecular Weight 338.309
Flash Point 233.9±25.0 °C
Exact Mass 338.100159
PSA 129.59000
LogP -0.46
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.641

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R26/27/28
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~93%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Organic and Biomolecular Chemistry, , vol. 4, # 24 p. 4453 - 4459

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of the Chemical Society, Perkin Transactions 1, , # 14 p. 2187 - 2193

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8271 - 8277

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 24 p. 8271 - 8277

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Collection of Czechoslovak Chemical Communications, , vol. 24, p. 1099,1102

~%

4-Methylumbelliferyl β-D-galactoside Structure

4-Methylumbelli...

CAS#:6160-78-7

Literature: Molecular Pharmacology, , vol. 79, # 3 p. 472 - 478

 Articles49

More Articles
Maternal immune activation in late gestation increases neuroinflammation and aggravates experimental autoimmune encephalomyelitis in the offspring.

Brain. Behav. Immun. 43 , 159-71, (2014)

Multiple sclerosis (MS) is characterized by an autoimmune response against myelin antigens driven by autoreactive T cells. Several lines of evidence indicate that environmental factors, such as previo...

Effect-directed analysis of cold-pressed hemp, flax and canola seed oils by planar chromatography linked with (bio)assays and mass spectrometry.

Food Chem. 187 , 460-8, (2015)

Cold-pressed hemp, flax and canola seed oils are healthy oils for human consumption as these are rich in polyunsaturated fatty acids and bioactive phytochemicals. However, bioactive information on the...

Contrasting growth responses in lamina and petiole during neighbor detection depend on differential auxin responsiveness rather than different auxin levels.

New Phytol. 208 , 198-209, (2015)

Foliar shade triggers rapid growth of specific structures that facilitate access of the plant to direct sunlight. In leaves of many plant species, this growth response is complex because, although sha...

 Synonyms

2H-1-Benzopyran-2-one, 7-(β-D-galactopyranosyloxy)-4-methyl-
4-Methylumbelliferyl β-D-galactoside
4-Methyl-2-oxo-2H-chromen-7-yl β-D-galactopyranoside
EINECS 228-185-5
4-methyl-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
MFCD00036773