4-methylumbelliferyl β-D-glucoside

Modify Date: 2024-01-02 15:49:38

4-methylumbelliferyl β-D-glucoside Structure
4-methylumbelliferyl β-D-glucoside structure
Common Name 4-methylumbelliferyl β-D-glucoside
CAS Number 18997-57-4 Molecular Weight 338.309
Density 1.5±0.1 g/cm3 Boiling Point 626.9±55.0 °C at 760 mmHg
Molecular Formula C16H18O8 Melting Point 258-263ºC (dec.)
MSDS USA Flash Point 233.9±25.0 °C

 Use of 4-methylumbelliferyl β-D-glucoside


4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2].

 Names

Name 4-Methylumbelliferyl-β-D-glucopyranoside
Synonym More Synonyms

 4-methylumbelliferyl β-D-glucoside Biological Activity

Description 4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2].
Related Catalog
Target

4-Methylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase[1].

References

[1]. Smitka CM,et al. Rapid fluorogenic assay for differentiation of the Candida parapsilosis group from other Candida spp. J Clin Microbiol. 1989;27(1):203-206.

[2]. Oftedal L, et al. Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid. Sci Rep. 2020;10(1):22098. Published 2020 Dec 16.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 626.9±55.0 °C at 760 mmHg
Melting Point 258-263ºC (dec.)
Molecular Formula C16H18O8
Molecular Weight 338.309
Flash Point 233.9±25.0 °C
Exact Mass 338.100159
PSA 129.59000
LogP -0.46
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.641
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
Risk Phrases 26/27/28
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

7-hydroxy-4-methyl-8-nitro-chromen-2-one
4-methylumbelliferyl β-D-glucoside
4-Methyl-2-oxo-2H-chromen-7-yl β-D-glucopyranoside
4-methyl-7-hydroxy-8-nitro coumarin
EINECS 228-185-5
4-methyl-8-nitro-7-hydroxycoumarin
4-Methylumbelliferyl-beta-D-glucopyranoside
MFCD00036773
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-4-methyl-
mutanolysin
7-Hydroxy-4-methyl-8-nitro-cumarin
(4-Methylumbelliferone)-β-D-glucopyranoside
7-hydroxy-4-methyl-8-nitro-coumarin
7-hydroxy-8-nitro-4-methyl-2H-chromen-2-one
4-Methylumbelliferyl β-D-glucopyranoside