Temocillin disodium salt

Modify Date: 2024-01-21 11:33:52

Temocillin disodium salt structure	Common Name	Temocillin disodium salt
	CAS Number	61545-06-0	Molecular Weight	458.42
	Density	1.6g/cm3	Boiling Point	761.9ºC at 760mmHg
	Molecular Formula	C₁₆H₁₆N₂Na₂O₇S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	414.6ºC

Use of Temocillin disodium salt

Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity[1].

Name	temocillin disodium
Synonym	More Synonyms

Description	Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vivo	Temocillin dosing regimens of 200 mg/kg every 4 and 6 h remained significantly effective in reducing bacterial titres in kidneys against the two strains, with no significant difference between the parental strain and its transconjugant[2].
References	[1]. K Jules, et al. Antibacterial activity and beta-lactamase stability of temocillin. Antimicrob Agents Chemother. 1982 Sep;22(3):453-60. [2]. J F Soubirou, et al. Activity of temocillin in a murine model of urinary tract infection due to Escherichia coli producing or not producing the ESBL CTX-M-15. J Antimicrob Chemother. 2015 May;70(5):1466-72.

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,6-((carboxy-3-thienylacetyl)amino)-6-methoxy-3,3-dimethyl-7-oxo-,disodium salt,(2S,5R,6S)

disodium,(2S,5R,6S)-6-[(2-carboxylato-2-thiophen-3-ylacetyl)amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

UNII-96IIP39ODH

Negaban (TN)

Temocillin disodium salt

EINECS 262-835-9

Temocillin sodium

Temocillin

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