5-Ethynyl-2'-deoxyuridine structure
|
Common Name | 5-Ethynyl-2'-deoxyuridine | ||
|---|---|---|---|---|
| CAS Number | 61135-33-9 | Molecular Weight | 252.22300 | |
| Density | 1.55g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C11H12N2O5 | Melting Point | 199 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS08 |
Signal Word | Danger | |
Use of 5-Ethynyl-2'-deoxyuridine5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 5-Ethynyl-2′-deoxyuridine, (EdU) |
|---|---|
| Synonym | More Synonyms |
| Description | 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.55g/cm3 |
|---|---|
| Melting Point | 199 °C |
| Molecular Formula | C11H12N2O5 |
| Molecular Weight | 252.22300 |
| Exact Mass | 252.07500 |
| PSA | 104.55000 |
| Index of Refraction | 1.644 |
| InChIKey | CDEURGJCGCHYFH-DJLDLDEBSA-N |
| SMILES | C#Cc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
|
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H340-H361 |
| Precautionary Statements | P201-P281-P308 + P313 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| Precursor 8 | |
|---|---|
| DownStream 5 | |
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| 5-ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| 5-Ethynyl-2'-deoxyuridine |