CB-002 structure
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Common Name | CB-002 | ||
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CAS Number | 61034-15-9 | Molecular Weight | 271.27500 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C13H13N5O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of CB-002CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells. |
Name | 8-anilino-1,3-dimethyl-7H-purine-2,6-dione |
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Synonym | More Synonyms |
Molecular Formula | C13H13N5O2 |
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Molecular Weight | 271.27500 |
Exact Mass | 271.10700 |
PSA | 87.94000 |
LogP | 0.12580 |
8-Anilino-1,3-dimethyl-3,7-dihydro-purin-2,6-dion |
8-Phenylaminotheophyllin |
8-anilino-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione |
8-Anilino-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione |
8-phenylaminotheophylline |
8-anilino-1,3-dimethyl-3,7-dihydro-purine-2,6-dione |
1H-purine-2,6-dione,3,7-dihydro-1,3-dimethyl-8-(phenylamino) |
8-anilino-1,3-dimethyl-3,7(9)-dihydro-purine-2,6-dione |