CB-002
Modify Date: 2025-08-22 19:30:05
CB-002 structure
|
Common Name | CB-002 | ||
|---|---|---|---|---|
| CAS Number | 61034-15-9 | Molecular Weight | 271.27500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H13N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CB-002CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells. |
| Name | 8-anilino-1,3-dimethyl-7H-purine-2,6-dione |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C13H13N5O2 |
|---|---|
| Molecular Weight | 271.27500 |
| Exact Mass | 271.10700 |
| PSA | 87.94000 |
| LogP | 0.12580 |
| 8-Anilino-1,3-dimethyl-3,7-dihydro-purin-2,6-dion |
| 8-Phenylaminotheophyllin |
| 8-anilino-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione |
| 8-Anilino-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione |
| 8-phenylaminotheophylline |
| 8-anilino-1,3-dimethyl-3,7-dihydro-purine-2,6-dione |
| 1H-purine-2,6-dione,3,7-dihydro-1,3-dimethyl-8-(phenylamino) |
| 8-anilino-1,3-dimethyl-3,7(9)-dihydro-purine-2,6-dione |