CB-002

• 常用名: CB-002
• 英文名: CB-002
• CAS号: 61034-15-9
• 分子量: 271.27500
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₃N₅O₂
• 熔点: N/A
• 闪点: N/A

CB-002用途

CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells.

CB-002名称

• 英文名: 8-anilino-1,3-dimethyl-7H-purine-2,6-dione

CB-002物理化学性质

• 分子式: C₁₃H₁₃N₅O₂
• 分子量: 271.27500
• 精确质量: 271.10700
• PSA: 87.94000
• LogP: 0.12580

CB-002英文别名

• 8-Anilino-1,3-dimethyl-3,7-dihydro-purin-2,6-dion
• 8-Phenylaminotheophyllin
• 8-anilino-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• 8-Anilino-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione
• 8-phenylaminotheophylline
• 8-anilino-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
• 1H-purine-2,6-dione,3,7-dihydro-1,3-dimethyl-8-(phenylamino)
• 8-anilino-1,3-dimethyl-3,7(9)-dihydro-purine-2,6-dione