Sesamin
Sesamin structure
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Common Name | Sesamin | ||
|---|---|---|---|---|
| CAS Number | 607-80-7 | Molecular Weight | 354.353 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 504.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H18O6 | Melting Point | 122-124ºC | |
| MSDS | Chinese USA | Flash Point | 212.3±30.0 °C | |
Use of SesaminSesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. |
| Name | (+)-sesamin |
|---|---|
| Synonym | More Synonyms |
| Description | Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. |
|---|---|
| Related Catalog | |
| Target |
delta 5 desaturase[1] |
| In Vitro | Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated[1]. |
| In Vivo | Sesamin (o.p.; 20 mg/kg/day) significantly reduces the infarct size by approximately 50% in male gerbils (60-85 g)[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 504.4±50.0 °C at 760 mmHg |
| Melting Point | 122-124ºC |
| Molecular Formula | C20H18O6 |
| Molecular Weight | 354.353 |
| Flash Point | 212.3±30.0 °C |
| Exact Mass | 354.110352 |
| PSA | 55.38000 |
| LogP | 3.32 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.623 |
| InChIKey | PEYUIKBAABKQKQ-AFHBHXEDSA-N |
| SMILES | c1cc2c(cc1C1OCC3C(c4ccc5c(c4)OCO5)OCC13)OCO2 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932999099 |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition.
Sci. Rep. 4 , 5896, (2014) Dysfunctions of the mitochondria and the ubiquitin-proteasome system, as well as generation of reactive oxygen species (ROS), are linked to many aging-related neurodegenerative disorders. However, the... |
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Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Mol. Biol. Rep. 39(6) , 6867-73, (2012) Metabolic transformations of two substrates for human cytochrome P450 (CYP450) 2C9, tolbutamide and diclofenac, were investigated in hepatic microsomes from Atlantic salmon (Salmo salar L.). Tolbutami... |
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Influence of oral supplementation with sesamin on longevity of Caenorhabditis elegans and the host defense.
Eur. J. Nutr. 53(8) , 1659-68, (2014) Nutritional control has been proposed as a potential therapy for slowing the senescence of immune function and decreasing mortality. This study investigated whether sesamin could modify host defense s... |
| Sesamin |
| (7S,7’S,8R,8’R)-sesamin |
| 5,5'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole) |
| (+)-Sesamin |
| Pseudocubebin |
| d-Sesamin |
| SesameP.E. |
| SezaMin |
| 1,3-Benzodioxole, 5,5'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis- |
| FAGAROL |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Sesamin
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Sesamin
- Price: ￥98.0/20mg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Sesamin
- Price: $280.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: TIANFU-CHEM -Sesamin
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
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