Sesamin

Modify Date: 2024-01-09 17:51:21

Sesamin structure	Common Name	Sesamin
	CAS Number	607-80-7	Molecular Weight	354.353
	Density	1.4±0.1 g/cm3	Boiling Point	504.4±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₈O₆	Melting Point	122-124ºC
	MSDS	Chinese USA	Flash Point	212.3±30.0 °C

Use of Sesamin

Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].

Name	(+)-sesamin
Synonym	More Synonyms

Description	Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	delta 5 desaturase[1]
In Vitro	Pretreated with sesamin, Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated[1].
In Vivo	Sesamin (o.p.; 20 mg/kg/day) significantly reduces the infarct size by approximately 50% in male gerbils (60-85 g)[1].
References	[1]. Cheng FC, et al. Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. Int J Biomed Sci. 2006 Sep;2(3):284-8. [2]. Shimizu S, et al. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acidbiosynthesis. Lipids. 1991 Jul;26(7):512-6.

Density	1.4±0.1 g/cm3
Boiling Point	504.4±50.0 °C at 760 mmHg
Melting Point	122-124ºC
Molecular Formula	C₂₀H₁₈O₆
Molecular Weight	354.353
Flash Point	212.3±30.0 °C
Exact Mass	354.110352
PSA	55.38000
LogP	3.32
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.623
Storage condition	−20°C

Sesamin MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).

Mol. Biol. Rep. 39(6) , 6867-73, (2012)

Metabolic transformations of two substrates for human cytochrome P450 (CYP450) 2C9, tolbutamide and diclofenac, were investigated in hepatic microsomes from Atlantic salmon (Salmo salar L.). Tolbutami...

Influence of oral supplementation with sesamin on longevity of Caenorhabditis elegans and the host defense.

Eur. J. Nutr. 53(8) , 1659-68, (2014)

Nutritional control has been proposed as a potential therapy for slowing the senescence of immune function and decreasing mortality. This study investigated whether sesamin could modify host defense s...

Sesamin

(7S,7’S,8R,8’R)-sesamin

5,5'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole)

(+)-Sesamin

Pseudocubebin

d-Sesamin

SesameP.E.

SezaMin

1,3-Benzodioxole, 5,5'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis-

FAGAROL

BioBioPha
China
Product Name: Sesamin
Price: ￥Inquiry/50mg
Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sesamin
Price: ￥98.0/20mg
Purity: 98.0%
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DC Chemicals Limited
China
Product Name: Sesamin
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
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Zhejiang Hangyu API Co., Ltd
China
Product Name: TIANFU-CHEM -Sesamin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU-CHEM -Sesamin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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