MtbHU-IN-1

Modify Date: 2024-01-03 14:06:45

MtbHU-IN-1 Structure
MtbHU-IN-1 structure
Common Name MtbHU-IN-1
CAS Number 59736-84-4 Molecular Weight 876.91
Density N/A Boiling Point N/A
Molecular Formula C44H36N4O12S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MtbHU-IN-1


MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.

 Names

Name MtbHU-IN-1

 MtbHU-IN-1 Biological Activity

Description MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.
Related Catalog
Target

Kd: 98 nM (WT MtbHU )[1].

In Vitro MtbHU-IN-1 (SD4) is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with Kds of 98 nM, 760 nM, 980 nM, 340 nM and 730 nM for WT and mutant MtbHUs, respectively[1].
References

[1]. Bhowmick T, et al. Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors. Nat Commun. 2014 Jun 11;5:4124.

 Chemical & Physical Properties

Molecular Formula C44H36N4O12S2
Molecular Weight 876.91
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