4',5'-DIBROMOFLUORESCEIN

Modify Date: 2024-01-19 17:58:48

4',5'-DIBROMOFLUORESCEIN Structure
4',5'-DIBROMOFLUORESCEIN structure
Common Name 4',5'-DIBROMOFLUORESCEIN
CAS Number 596-03-2 Molecular Weight 490.09800
Density 2.1 g/cm3 Boiling Point 633.7ºC at 760 mmHg
Molecular Formula C20H10Br2O5 Melting Point 270-273 °C(lit.)
MSDS Chinese USA Flash Point 337ºC
Symbol GHS06
GHS06
Signal Word Danger

 Use of 4',5'-DIBROMOFLUORESCEIN


4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].

 Names

Name 4',5'-Dibromofluorescein
Synonym More Synonyms

 4',5'-DIBROMOFLUORESCEIN Biological Activity

Description 4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].
Related Catalog
References

[1]. Dongdong Yu, et al. An ultrasensitive stain for negative protein detection in SDS-PAGE via 4',5'-Dibromofluorescein. J Proteomics. 2017 Aug 8;165:21-25.

 Chemical & Physical Properties

Density 2.1 g/cm3
Boiling Point 633.7ºC at 760 mmHg
Melting Point 270-273 °C(lit.)
Molecular Formula C20H10Br2O5
Molecular Weight 490.09800
Flash Point 337ºC
Exact Mass 487.88900
PSA 75.99000
LogP 5.19080
Index of Refraction 1.771

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5200000
CHEMICAL NAME :
Fluorescein, 4',5'-dibromo-
CAS REGISTRY NUMBER :
596-03-2
BEILSTEIN REFERENCE NO. :
0057189
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H10-Br2-O5
MOLECULAR WEIGHT :
490.12
WISWESSER LINE NOTATION :
T C666 BO EVJ DE IR BVQ& MQ NE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15556 mg/kg/21D-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ng/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,116,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1904 No. of Facilities: 237 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 6161 (estimated) No. of Female Employees: 474 (estimated)

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xi: Irritant;
Risk Phrases R36
Safety Phrases S22-S24/25-S45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS LM5200000
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD00005042
EINECS 209-876-0
4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one