C7280948
Modify Date: 2025-08-27 07:46:43
C7280948 structure
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Common Name | C7280948 | ||
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| CAS Number | 587850-67-7 | Molecular Weight | 276.354 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 481.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C14H16N2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 244.8±31.5 °C | |
Use of C7280948C-7280948 is a PRMT1 inhibitor.IC50 value:Target: PRMT1in vitro: Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1. |
| Name | 4-amino-N-(2-phenylethyl)benzenesulfonamide |
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| Synonym | More Synonyms |
| Description | C-7280948 is a PRMT1 inhibitor.IC50 value:Target: PRMT1in vitro: Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 481.1±55.0 °C at 760 mmHg |
| Molecular Formula | C14H16N2O2S |
| Molecular Weight | 276.354 |
| Flash Point | 244.8±31.5 °C |
| Exact Mass | 276.093262 |
| PSA | 80.57000 |
| LogP | 2.18 |
| Appearance of Characters | white solid |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.617 |
| Storage condition | -20℃ |
| HS Code | 2935009090 |
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~88%
C7280948 CAS#:587850-67-7 |
| Literature: Bissinger, Elisabeth-Maria; Heinke, Ralf; Spannhoff, Astrid; Eberlin, Adrien; Metzger, Eric; Cura, Vincent; Hassenboehler, Pierre; Cavarelli, Jean; Schuele, Roland; Bedford, Mark T.; Sippl, Wolfgang; Jung, Manfred Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 12 p. 3717 - 3731 |
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C7280948 CAS#:587850-67-7 |
| Literature: Journal of the Indian Chemical Society, , vol. 18, p. 316,319 |
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C7280948 CAS#:587850-67-7 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 19, # 12 p. 3717 - 3731 |
|
~%
C7280948 CAS#:587850-67-7 |
| Literature: Journal of the Indian Chemical Society, , vol. 18, p. 316,319 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
| sulfanilic acid phenethylamide |
| Sulfanilsaeure-phenaethylamid |
| 4-amino-N-phenethylbenzenesulfonamide |
| 4-Amino-N-(2-phenylethyl)benzenesulfonamide |
| Benzenesulfonamide, 4-amino-N-(2-phenylethyl)- |
| C7280948 |
| C-7280948 |