Licochalcone B structure
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Common Name | Licochalcone B | ||
|---|---|---|---|---|
| CAS Number | 58749-23-8 | Molecular Weight | 286.279 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 550.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H14O5 | Melting Point | 196-197ºC | |
| MSDS | N/A | Flash Point | 208.5±23.6 °C | |
Use of Licochalcone BLicochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid β (Aβ42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ions[1]. |
| Name | (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | Licochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid β (Aβ42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ions[1]. |
|---|---|
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 550.5±50.0 °C at 760 mmHg |
| Melting Point | 196-197ºC |
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.279 |
| Flash Point | 208.5±23.6 °C |
| Exact Mass | 286.084137 |
| PSA | 86.99000 |
| LogP | 2.57 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.684 |
| Storage condition | 2-8C |
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Licochalcone B CAS#:58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
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Licochalcone B CAS#:58749-23-8 |
| Literature: Islam, Azizul; Khan, Saeed Ahmad; Krishnamurti, M. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 965 - 966 |
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Licochalcone B CAS#:58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
~%
Licochalcone B CAS#:58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
~%
Licochalcone B CAS#:58749-23-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
|
~%
Licochalcone B CAS#:58749-23-8 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 1 p. 181 - 185 |
| 2-methoxy-3,4,4'-trihydroxychalcone |
| Licochalcone B |
| Licochalcon B |
| (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one |
| 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- |
| licochalcone |