4-Bromo-2-fluorobenzaldehyde

Modify Date: 2025-08-23 23:48:05

4-Bromo-2-fluorobenzaldehyde Structure
4-Bromo-2-fluorobenzaldehyde structure
Common Name 4-Bromo-2-fluorobenzaldehyde
CAS Number 57848-46-1 Molecular Weight 203.008
Density 1.7±0.1 g/cm3 Boiling Point 241.4±25.0 °C at 760 mmHg
Molecular Formula C7H4BrFO Melting Point 59-64 °C
MSDS USA Flash Point 99.8±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Bromo-2-fluorobenzaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 241.4±25.0 °C at 760 mmHg
Melting Point 59-64 °C
Molecular Formula C7H4BrFO
Molecular Weight 203.008
Flash Point 99.8±23.2 °C
Exact Mass 201.942947
PSA 17.07000
LogP 2.71
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.585
Storage condition Room temperature.
Water Solubility INSOLUBLE

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S37/39-S26-S36
RIDADR NONH for all modes of transport
HS Code 2913000090

 Synthetic Route

~61%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: ANTHEM BIOSCIENCES PRIVATE LIMITED Patent: US2012/101099 A1, 2012 ; Location in patent: Page/Page column 13; 14 ;

~90%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: Iida, Takehiko; Wada, Toshihiro; Tomimoto, Koji; Mase, Toshiaki Tetrahedron Letters, 2001 , vol. 42, # 29 p. 4841 - 4844

~51%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: Wang, Guangjun; Li, Zhengwei; Ha, Chengyong; Ding, Ke Synthetic Communications, 2008 , vol. 38, # 10 p. 1629 - 1637

~%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 1 p. 279 - 282

~%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 1 p. 279 - 282

~%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: WO2011/21209 A1, ; WO 2011/021209 A1

~%

4-Bromo-2-fluorobenzaldehyde Structure

4-Bromo-2-fluor...

CAS#:57848-46-1

Literature: WO2011/21209 A1, ; WO 2011/021209 A1

 Customs

HS Code 2913000090
Summary HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

 Articles4

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Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors.

Arch. Pharm. (Weinheim) 344(6) , 372-85, (2011)

Aldose reductase (ARL2) is the first enzyme in the polyol pathway which catalyzes the NADPH-dependent reduction of glucose to sorbitol. Its involvement on diabetic complications makes this enzyme a ch...

Synthesis of tri-substituted biaryl based trianglimines: formation of C3-symmetrical and non-symmetrical regioisomers.

Org. Biomol. Chem. 9(9) , 3258-71, (2011)

2-Functionalised aromatic monoaldehydes were synthesised in good to excellent yields by reacting 4-bromo-2-fluorobenzaldehyde with different secondary amines and phenol. The Suzuki-coupling reaction o...

Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.

Bioorg. Med. Chem. Lett. 17(17) , 4799-803, (2007)

The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described.

 Synonyms

4-bromo-6-fluorobenzaldehyde
Benzaldehyde, 4-bromo-2-fluoro-
VHR BF DE
MFCD00143261
4-Brom-2-fluorbenzolcarbaldehyd
4-Bromo-2-fluorobenzaldehyde
2-Fluoro-4-bromobenzaldehyde
4-bromo2-fluorobenzaldehyde
benzaldehyde,4-bromo-2-fluoro
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