2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Modify Date: 2025-09-02 20:10:46

2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol Structure
2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol structure
Common Name 2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
CAS Number 5746-27-0 Molecular Weight 282.26
Density 2.12g/cm3 Boiling Point 723.5ºC at 760mmHg
Molecular Formula C10H14N6O4 Melting Point N/A
MSDS N/A Flash Point 391.4ºC

 Use of 2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol


N6-Aminoadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name 9H-Purine, 6-hydrazino-9-.β.-D-ribofuranosyl
Synonym More Synonyms

  Biological Activity

Description N6-Aminoadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Density 2.12g/cm3
Boiling Point 723.5ºC at 760mmHg
Molecular Formula C10H14N6O4
Molecular Weight 282.26
Flash Point 391.4ºC
Exact Mass 282.10800
PSA 154.80000
InChIKey DGKZTAGCCXJUAT-KQYNXXCUSA-N
SMILES NNc1ncnc2c1ncn2C1OC(CO)C(O)C1O

 Synonyms

7-benzyl-6-hydrazino-7H-purine
6-Hydrazino-7-benzyl-7H-purin
N6-hydrazinoadenosine
7-benzyl-6-hydrazinyl-7h-purine
N6-aminoadenosine
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