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2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

[ CAS No. ]:
5746-27-0

[ Name ]:
2-(6-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

[Synonym ]:
7-benzyl-6-hydrazino-7H-purine
6-Hydrazino-7-benzyl-7H-purin
N6-hydrazinoadenosine
7-benzyl-6-hydrazinyl-7h-purine
N6-aminoadenosine

Biological Activity

[Description]:

N6-Aminoadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Density]:
2.12g/cm3

[ Boiling Point ]:
723.5ºC at 760mmHg

[ Molecular Formula ]:
C10H14N6O4

[ Molecular Weight ]:
282.26

[ Flash Point ]:
391.4ºC

[ Exact Mass ]:
282.10800

[ PSA ]:
154.80000

Precursor & DownStream


Related Compounds

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