(9R)-6'-methoxycinchonan-9-ol

Modify Date: 2024-01-02 18:05:11

(9R)-6'-methoxycinchonan-9-ol Structure
(9R)-6'-methoxycinchonan-9-ol structure
Common Name (9R)-6'-methoxycinchonan-9-ol
CAS Number 572-59-8 Molecular Weight 324.41700
Density 1.218g/cm3 Boiling Point 495.88ºC at 760 mmHg
Molecular Formula C20H24N2O2 Melting Point 111-113°
MSDS Chinese USA Flash Point 253.699ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

 Use of (9R)-6'-methoxycinchonan-9-ol


Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM[1].

 Names

Name (R)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Synonym More Synonyms

 (9R)-6'-methoxycinchonan-9-ol Biological Activity

Description Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM[1].
Related Catalog
Target

ggTas2r1[1]

References

[1]. Pizio AD, et, al. Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep. 2017 Aug 15;7(1):8223.

 Chemical & Physical Properties

Density 1.218g/cm3
Boiling Point 495.88ºC at 760 mmHg
Melting Point 111-113°
Molecular Formula C20H24N2O2
Molecular Weight 324.41700
Flash Point 253.699ºC
Exact Mass 324.18400
PSA 45.59000
LogP 3.11110
Index of Refraction 1.638

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H302-H317-H334
Precautionary Statements P261-P280-P342 + P311
Hazard Codes Xn
Risk Phrases 22-42/43
Safety Phrases 22-36/37-45
RIDADR NONH for all modes of transport

 Synonyms

GNF-Pf-180
9-epi-Quinidine
Epiquinidine