(9R)-6'-methoxycinchonan-9-ol

Names

[ CAS No. ]:
572-59-8

[ Name ]:
(9R)-6'-methoxycinchonan-9-ol

[Synonym ]:
GNF-Pf-180
9-epi-Quinidine
Epiquinidine

Biological Activity

[Description]:

Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

ggTas2r1[1]

[References]

[1]. Pizio AD, et, al. Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep. 2017 Aug 15;7(1):8223.

Chemical & Physical Properties

[ Density]:
1.218g/cm3

[ Boiling Point ]:
495.88ºC at 760 mmHg

[ Melting Point ]:
111-113°

[ Molecular Formula ]:
C₂₀H₂₄N₂O₂

[ Molecular Weight ]:
324.41700

[ Flash Point ]:
253.699ºC

[ Exact Mass ]:
324.18400

[ PSA ]:
45.59000

[ LogP ]:
3.11110

[ Index of Refraction ]:
1.638

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H317-H334

[ Precautionary Statements ]:
P261-P280-P342 + P311

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-42/43

[ Safety Phrases ]:
22-36/37-45

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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