Z-Leu-Tyr-chloromethylketone

Modify Date: 2025-09-18 16:13:32

Z-Leu-Tyr-chloromethylketone structure	Common Name	Z-Leu-Tyr-chloromethylketone
	CAS Number	56979-35-2	Molecular Weight	460.95000
	Density	1.231g/cm3	Boiling Point	693.5ºC at 760mmHg
	Molecular Formula	C₂₄H₂₉ClN₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	373.2ºC

Use of Z-Leu-Tyr-chloromethylketone

Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor[1].

Name	N2-[(Benzyloxy)carbonyl]-N-[(2S)-4-chloro-1-(4-hydroxyphenyl)-3-oxo-2-butanyl]-L-leucinamide

Description	Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	IC50: calpain[1]
References	[1]. L Ditzel, et al. Structural investigation of proteasome inhibition. Biol Chem. 1997 Mar-Apr;378(3-4):239-47.

Density	1.231g/cm3
Boiling Point	693.5ºC at 760mmHg
Molecular Formula	C₂₄H₂₉ClN₂O₅
Molecular Weight	460.95000
Flash Point	373.2ºC
Exact Mass	460.17600
PSA	111.71000
LogP	4.61320
Index of Refraction	1.566
InChIKey	BXNJBFCUDNXPPQ-UHFFFAOYSA-N
SMILES	CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)CCl

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