402474-85-5

402474-85-5 structure
402474-85-5 structure
  • Name: Z-Tyr-Val-Ala-Asp-chloromethylketone
  • Chemical Name: (5S,8S,11S,14S)-14-(Chloroacetyl)-3,6,9,12-tetrahydroxy-5-(4-hydroxybenzyl)-8-isopropyl-11-methyl-1-phenyl-2-oxa-4,7,10,13-tetraazahexadeca-3,6,9,12-tetraen-16-oic acid
  • CAS Number: 402474-85-5
  • Molecular Formula: C30H37ClN4O9
  • Molecular Weight: 633.09
  • Catalog: Signaling Pathways Apoptosis Caspase
  • Create Date: 2018-06-11 22:48:17
  • Modify Date: 2024-01-13 14:16:54
  • Z-YVAD-CMK is a caspase-1 and caspase-3 inhibitor[1].

Name (5S,8S,11S,14S)-14-(Chloroacetyl)-3,6,9,12-tetrahydroxy-5-(4-hydroxybenzyl)-8-isopropyl-11-methyl-1-phenyl-2-oxa-4,7,10,13-tetraazahexadeca-3,6,9,12-tetraen-16-oic acid
Synonyms (5S,8S,11S,14S)-14-(Chloroacetyl)-3,6,9,12-tetrahydroxy-5-(4-hydroxybenzyl)-8-isopropyl-11-methyl-1-phenyl-2-oxa-4,7,10,13-tetraazahexadeca-3,6,9,12-tetraen-16-oic acid
2-Oxa-4,7,10,13-tetraazahexadeca-3,6,9,12-tetraen-16-oic acid, 14-(2-chloroacetyl)-3,6,9,12-tetrahydroxy-5-[(4-hydroxyphenyl)methyl]-11-methyl-8-(1-methylethyl)-1-phenyl-, (5S,8S,11S,14S)-
Description Z-YVAD-CMK is a caspase-1 and caspase-3 inhibitor[1].
Related Catalog
Target

caspase-1, caspase-3[1]

References

[1]. Knies UE, et al. Regulation of endothelial monocyte-activating polypeptide II release by apoptosis. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12322-7.  

Density 1.4±0.1 g/cm3
Boiling Point 844.4±75.0 °C at 760 mmHg
Molecular Formula C30H37ClN4O9
Molecular Weight 633.09
Flash Point 464.5±37.1 °C
Exact Mass 632.224915
LogP 6.72
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.601