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Z-Leu-Tyr-chloromethylketone

Names

[ CAS No. ]:
56979-35-2

[ Name ]:
Z-Leu-Tyr-chloromethylketone

Biological Activity

[Description]:

Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[Target]

IC50: calpain[1]


[References]

[1]. L Ditzel, et al. Structural investigation of proteasome inhibition. Biol Chem. 1997 Mar-Apr;378(3-4):239-47.

Chemical & Physical Properties

[ Density]:
1.231g/cm3

[ Boiling Point ]:
693.5ºC at 760mmHg

[ Molecular Formula ]:
C24H29ClN2O5

[ Molecular Weight ]:
460.95000

[ Flash Point ]:
373.2ºC

[ Exact Mass ]:
460.17600

[ PSA ]:
111.71000

[ LogP ]:
4.61320

[ Index of Refraction ]:
1.566

Related Compounds