UBP301

Modify Date: 2025-08-25 13:56:18

UBP301 Structure
UBP301 structure
 Common Name UBP301
CAS Number 569371-10-4 Molecular Weight 459.19300
Density N/A Boiling Point N/A
Molecular Formula C15H14IN3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UBP301


UBP301 is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 has ∼30-fold selectivity of kainate receptor over AMPA receptor. UBP301 is the derivative of willardiine[1].

 Names

Name UBP 301,(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoicacid
Synonym More Synonyms

 UBP301 Biological Activity

Description UBP301 is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 has ∼30-fold selectivity of kainate receptor over AMPA receptor. UBP301 is the derivative of willardiine[1].
Related Catalog
Target

164 μM (kainate receptor)[1]

References

[1]. More JC, et al. Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br J Pharmacol. 2003;138(6):1093-1100.

 Chemical & Physical Properties

Molecular Formula C15H14IN3O6
Molecular Weight 459.19300
Exact Mass 458.99300
PSA 144.62000
LogP 0.47330

 Synonyms

ubp 301
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Chemsrc provides UBP301(CAS#:569371-10-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of UBP301 are included as well.>> amp version: UBP301

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