Moracin M
Modify Date: 2024-01-03 18:08:20
Moracin M structure
|
Common Name | Moracin M | ||
|---|---|---|---|---|
| CAS Number | 56317-21-6 | Molecular Weight | 242.227 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 369.3±22.0 °C at 760 mmHg | |
| Molecular Formula | C14H10O4 | Melting Point | 271-273 ºC | |
| MSDS | N/A | Flash Point | 177.1±22.3 °C | |
Use of Moracin MMoracin M, a phenolic component in the skin of Morus alba L., is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1]. |
| Name | 5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol |
|---|---|
| Synonym | More Synonyms |
| Description | Moracin M, a phenolic component in the skin of Morus alba L., is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1]. |
|---|---|
| Target |
PDE4D2:2.9 μM (IC50) PDE4B2:4.5 μM (IC50) PDE5A1:>40 μM (IC50) PDE9A2:>100 μM (IC50) Human Endogenous Metabolite |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 369.3±22.0 °C at 760 mmHg |
| Melting Point | 271-273 ºC |
| Molecular Formula | C14H10O4 |
| Molecular Weight | 242.227 |
| Flash Point | 177.1±22.3 °C |
| Exact Mass | 242.057907 |
| PSA | 73.83000 |
| LogP | 2.37 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.730 |
| Water Solubility | Very slightly soluble (0.18 g/L) (25 ºC) |
| Hazard Codes | Xi |
|---|
| Precursor 9 | |
|---|---|
| DownStream 0 | |
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CAS#:13196-11-7| 1,3-Benzenediol, 5-(6-hydroxy-2-benzofuranyl)- |
| Veraphenol |
| 5-(6-Hydroxy-benzofuran-2-yl)-benzene-1,3-diol |
| Moracin M |
| 5-(6-Hydroxy-1-benzofuran-2-yl)-1,3-benzenediol |
| 5-(6-Hydroxy-1-benzofuran-2-yl)benzene-1,3-diol |
| 2-(3,5-Dihydroxyphenyl)-6-hydroxybenzofuran |