56317-21-6
56317-21-6 structure
- Name: Moracin M
- Chemical Name: 5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol
- CAS Number: 56317-21-6
- Molecular Formula: C14H10O4
- Molecular Weight: 242.227
- Catalog: Natural product Phenols
- Create Date: 2017-11-10 13:52:29
- Modify Date: 2025-08-25 05:52:04
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Moracin M, a phenolic component in the skin of Morus alba L., is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1].
| Name | 5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol |
|---|---|
| Synonyms |
1,3-Benzenediol, 5-(6-hydroxy-2-benzofuranyl)-
Veraphenol 5-(6-Hydroxy-benzofuran-2-yl)-benzene-1,3-diol Moracin M 5-(6-Hydroxy-1-benzofuran-2-yl)-1,3-benzenediol 5-(6-Hydroxy-1-benzofuran-2-yl)benzene-1,3-diol 2-(3,5-Dihydroxyphenyl)-6-hydroxybenzofuran |
| Description | Moracin M, a phenolic component in the skin of Morus alba L., is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1]. |
|---|---|
| Target |
PDE4D2:2.9 μM (IC50) PDE4B2:4.5 μM (IC50) PDE5A1:>40 μM (IC50) PDE9A2:>100 μM (IC50) Human Endogenous Metabolite |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 369.3±22.0 °C at 760 mmHg |
| Melting Point | 271-273 ºC |
| Molecular Formula | C14H10O4 |
| Molecular Weight | 242.227 |
| Flash Point | 177.1±22.3 °C |
| Exact Mass | 242.057907 |
| PSA | 73.83000 |
| LogP | 2.37 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.730 |
| Water Solubility | Very slightly soluble (0.18 g/L) (25 ºC) |
| Hazard Codes | Xi |
|---|
| Precursor 9 | |
|---|---|
| DownStream 0 | |
![(E)-β-[2-hydroxy-4-benzyloxyphenylethylene]-3,5-dibenzyloxybenzeneethanol structure](https://image.chemsrc.com/caspic/148/863310-61-6.png)
