56317-21-6

56317-21-6 structure

Name: Moracin M
Chemical Name: 5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol
CAS Number: 56317-21-6
Molecular Formula: C₁₄H₁₀O₄
Molecular Weight: 242.227
Catalog: Natural product Phenols
Create Date: 2017-11-10 13:52:29
Modify Date: 2024-01-03 18:08:20
Moracin M, a phenolic component in the skin of Morus alba L., is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1].

Name	5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol
Synonyms	1,3-Benzenediol, 5-(6-hydroxy-2-benzofuranyl)- Veraphenol 5-(6-Hydroxy-benzofuran-2-yl)-benzene-1,3-diol Moracin M 5-(6-Hydroxy-1-benzofuran-2-yl)-1,3-benzenediol 5-(6-Hydroxy-1-benzofuran-2-yl)benzene-1,3-diol 2-(3,5-Dihydroxyphenyl)-6-hydroxybenzofuran

Description	Moracin M, a phenolic component in the skin of Morus alba L., is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity[1].
Target	PDE4D2:2.9 μM (IC50) PDE4B2:4.5 μM (IC50) PDE5A1:>40 μM (IC50) PDE9A2:>100 μM (IC50) Human Endogenous Metabolite
References	[1]. Chen SK, et al. Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor. Bioorg Med Chem Lett. 2012 May 1;22(9):3261-4.

Hazard Codes	Xi