CHIR 98014

Modify Date: 2024-01-11 17:53:08

CHIR 98014 Structure
CHIR 98014 structure
Common Name CHIR 98014
CAS Number 556813-39-9 Molecular Weight 486.314
Density 1.6±0.1 g/cm3 Boiling Point 839.0±75.0 °C at 760 mmHg
Molecular Formula C20H17Cl2N9O2 Melting Point N/A
MSDS N/A Flash Point 461.2±37.1 °C

 Use of CHIR 98014


CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM[1].

 Names

Name 6-N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine
Synonym More Synonyms

 CHIR 98014 Biological Activity

Description CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM[1].
Related Catalog
Target

GSK-3:0.2566 μM (EC50)

References

[1]. Stephen D. Harrison, et al. Methods and compositions for the treatment of ischemia. WO2003074072A1.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 839.0±75.0 °C at 760 mmHg
Molecular Formula C20H17Cl2N9O2
Molecular Weight 486.314
Flash Point 461.2±37.1 °C
Exact Mass 485.088226
PSA 163.25000
LogP 3.76
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.753

 Synonyms

2,6-Pyridinediamine, N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-
N-(2-{[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino}ethyl)-3-nitro-2,6-pyridinediamine
CHIR-98014
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  • DC Chemicals Limited
  • China
  • Product Name: CHIR98014
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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