Neutral Red

Modify Date: 2024-01-02 09:45:35

Neutral Red structure	Common Name	Neutral Red
	CAS Number	553-24-2	Molecular Weight	288.775
	Density	N/A	Boiling Point	497.3ºC at 760mmHg
	Molecular Formula	C₁₅H₁₇ClN₄	Melting Point	290 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	N/A

Use of Neutral Red

Neutral Red, a nitrogenous pH-indicator with a pKi of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red[1].

Name	neutral red
Synonym	More Synonyms

Description	Neutral Red, a nitrogenous pH-indicator with a pKi of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	As cells begin to die, their ability to incorporate neutral red diminishes. The neutral red is also used to stain cell cultures for plate titration of viruses[2].
References	[1]. Winfried AUSLANDER, et al. NEUTRAL RED, A RAPID INDICATOR FOR pH-CHANGES IN THE INNER PHASE OF THYLAKOIDS. FEBS LETTERS. 1975 Nov. [2]. Ellen Borenfreund, et al. A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90). Journal of tissue culture methods volume 9, pages7–9 (1985).

Boiling Point	497.3ºC at 760mmHg
Melting Point	290 °C (dec.)(lit.)
Molecular Formula	C₁₅H₁₇ClN₄
Molecular Weight	288.775
Exact Mass	288.114166
PSA	55.04000
LogP	4.12280
Water Solubility	50 g/L

Neutral Red MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1400000

CHEMICAL NAME :: Phenazine, 3-amino-7-(dimethylamino)-2-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 553-24-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C15-H16-N4.Cl-H

MOLECULAR WEIGHT :: 288.81

WISWESSER LINE NOTATION :: T C666 BN INJ E1 FZ LN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 432 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 142 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 96600 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Sister chromatid exchange

TYPE OF TEST :: DNA damage

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Bird - chicken

DOSE/DURATION :: 85 ug/kg

REFERENCE :: 47JMAE "Cytogenetic Assays of Environmental Mutagens," Hsu, T.C., ed., Totowa, NJ, Allanheld, Osmun & Co., 1982 Volume(issue)/page/year: -,137,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1598 No. of Facilities: 420 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 694 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1598 No. of Facilities: 746 (estimated) No. of Industries: 13 No. of Occupations: 12 No. of Employees: 23740 (estimated) No. of Female Employees: 19202 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R68
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SG1400000
HS Code	32041300

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Phenolics from Caesalpinia ferrea Mart.: antioxidant, cytotoxic and hypolipidemic activity.

Pharmazie 70 , 553-8, (2015)

Nine phenolics were isolated from the aqueous ethanol extract of the leaves of Caesalpinia ferrea. The isolates were characterized for the first time from that plant. The structures of all isolates (1...

N2,N2,7-Trimethylphenazine-2,8-diamine hydrochloride

3-amino-7-dimethylamino-2-methyl-phenazinium chloride

Nuclear Fast Red

NEUTRAL RED

Neutral Red W

Toluylene Red

Neutral Red chloride

3-Amino-7-dimethylamino-2-methylphenazine hydrochloride

2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride

Michrome No. 226

Neutral Red (Tautomer)

Basic Red 5

EINECS 209-035-8

8-N,8-N,3-trimethylphenazine-2,8-diamine,hydrochloride

Neutral Red Base

N8,N8,3-trimethyl-2,8-phenazinediamine monohydrochloride

C.I. Basic Red 5

N,N,3-Trimethylphenazine-2,8-diamine hydrochloride (1:1)

2,8-Phenazinediamine, N,N,3-trimethyl-, hydrochloride (1:1)

N,N,3-Trimethyl-2,8-phenazinediamine hydrochloride (1:1)

N8,N8,3-trimethylphenazine-2,8-diamine hydrochloride

MFCD04119237

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Neutral Red
Price: ￥118.0/25g ￥318.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Neutral red
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Basic Red 5
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFUCHEM--High purity Basic Red 5 factory price
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Neutral Red

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HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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