9H-purine-2,6-dithiol

Modify Date: 2025-08-26 21:03:43

9H-purine-2,6-dithiol structure	Common Name	9H-purine-2,6-dithiol
	CAS Number	5437-25-2	Molecular Weight	184.24
	Density	1.8±0.1 g/cm3	Boiling Point	496.2±37.0 °C at 760 mmHg
	Molecular Formula	C₅H₄N₄S₂	Melting Point	>350 °C(lit.)
	MSDS	N/A	Flash Point	253.9±26.5 °C

Use of 9H-purine-2,6-dithiol

2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis[1].

Name	2,6-Dithiopurine
Synonym	More Synonyms

Description	2,6-Dithiopurine (2,6-Dimercaptopurine) is a nucleophilic scavenger for electrophilic carcinogens. 2,6-Dithiopurine abolishes both DNA adduct formation and the initiation of carcinogenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Stephen Boulware, et al. 2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog. Toxicol Appl Pharmacol. 2012 Sep 1;263(2):203-9.

Density	1.8±0.1 g/cm3
Boiling Point	496.2±37.0 °C at 760 mmHg
Melting Point	>350 °C(lit.)
Molecular Formula	C₅H₄N₄S₂
Molecular Weight	184.24
Flash Point	253.9±26.5 °C
Exact Mass	183.987732
PSA	132.06000
LogP	-0.60
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.890
Storage condition	−20°C
Water Solubility	slightly soluble

9H-purine-2,6-dithiol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO8475000

CHEMICAL NAME :: Purine-2,6-dithiol

CAS REGISTRY NUMBER :: 5437-25-2

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H4-N4-S2

MOLECULAR WEIGHT :: 184.25

WISWESSER LINE NOTATION :: T56 BM DN FN HNJ GSH ISH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03045

Safety Phrases	S24/25
WGK Germany	3
RTECS	UO8475000
HS Code	2933990090

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Precursor 7
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DownStream 7
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HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

MFCD00022644

9H-purine-2,6-dithiol

EINECS 226-608-8

1H-Purine-2,6-dithione, 3,9-dihydro-

2H-Purine-2-thione, 1,9-dihydro-6-mercapto-

3,7-dihydropurine-2,6-dithione

1H-purine-2,6-dithione, 3,7-dihydro-

6-Sulfanyl-1,9-dihydro-2H-purine-2-thione

3,7-Dihydro-1H-purine-2,6-dithione

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 9H-purine-2,6-dithiol
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 9H-purine-2,6-dithiol
Price: ￥1438.0/1g
Purity: 97.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,6-Dithiopurine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥350/250 mg

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9H-purine-2,6-dithiol

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