STX-681
Modify Date: 2023-01-15 12:39:18
STX-681 structure
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Common Name | STX-681 | ||
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| CAS Number | 537674-89-8 | Molecular Weight | 449.283 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H13BrN6O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STX-681A novel potent, orally active, dual-acting aromatase and steroid sulfatase (STS) inhibitor with ICI0 of 0.82 nM and 39 nM, respectively; significantly reduces plasma E2 levels, completely inhibits the growth of both MCF-7(STS) tumor growth and MCF-7(AROM) tumor in a xenograft nude mouse model. |
| Name | STX-681 |
|---|
| Description | A novel potent, orally active, dual-acting aromatase and steroid sulfatase (STS) inhibitor with ICI0 of 0.82 nM and 39 nM, respectively; significantly reduces plasma E2 levels, completely inhibits the growth of both MCF-7(STS) tumor growth and MCF-7(AROM) tumor in a xenograft nude mouse model. |
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| References | References 1. Foster PA, et al. Clin Cancer Res. 2008 Oct 15;14(20):6469-77. 2. Woo LW, et al. J Med Chem. 2007 Jul 26;50(15):3540-60. View Related Products by Target Steroid Sulfatase (STS) |
| Molecular Formula | C16H13BrN6O3S |
|---|---|
| Molecular Weight | 449.283 |