415974-72-0
415974-72-0 structure
- Name: STX-213
- Chemical Name: STX-213
- CAS Number: 415974-72-0
- Molecular Formula: C21H28N2O5S
- Molecular Weight: 420.524
- Create Date: 2020-01-11 16:08:50
- Modify Date: 2023-01-16 09:25:16
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An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM; completely inhibits liver and tumor STS activity, and fully inhibits growth of MCF-7STS tumors in vivo.
| Name | STX-213 |
|---|
| Description | An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM; completely inhibits liver and tumor STS activity, and fully inhibits growth of MCF-7STS tumors in vivo. |
|---|---|
| References | References 1. Foster PA, et al. Clin Cancer Res. 2006 Sep 15;12(18):5543-9. 2. Foster PA, et al. Breast Cancer Res Treat. 2008 Sep;111(1):129-38. 3. Foster PA, et al. Endocrinology. 2008 Aug;149(8):4035-42. 4. Foster PA, et al. Clin Cancer Res. 2008 Oct 15;14(20):6469-77. View Related Products by Target Steroid Sulfatase (STS) |
| Molecular Formula | C21H28N2O5S |
|---|---|
| Molecular Weight | 420.524 |