STX-213

Modify Date: 2023-01-16 09:25:16

STX-213 Structure
STX-213 structure
Common Name STX-213
CAS Number 415974-72-0 Molecular Weight 420.524
Density N/A Boiling Point N/A
Molecular Formula C21H28N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of STX-213


An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM; completely inhibits liver and tumor STS activity, and fully inhibits growth of MCF-7STS tumors in vivo.

 Names

Name STX-213

 STX-213 Biological Activity

Description An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM; completely inhibits liver and tumor STS activity, and fully inhibits growth of MCF-7STS tumors in vivo.
References References 1. Foster PA, et al. Clin Cancer Res. 2006 Sep 15;12(18):5543-9. 2. Foster PA, et al. Breast Cancer Res Treat. 2008 Sep;111(1):129-38. 3. Foster PA, et al. Endocrinology. 2008 Aug;149(8):4035-42. 4. Foster PA, et al. Clin Cancer Res. 2008 Oct 15;14(20):6469-77. View Related Products by Target Steroid Sulfatase (STS)

 Chemical & Physical Properties

Molecular Formula C21H28N2O5S
Molecular Weight 420.524