Vaccarin

Modify Date: 2024-01-02 11:34:28

Vaccarin structure	Common Name	Vaccarin
	CAS Number	53452-16-7	Molecular Weight	726.633
	Density	1.8±0.1 g/cm3	Boiling Point	1088.1±65.0 °C at 760 mmHg
	Molecular Formula	C₃₂H₃₈O₁₉	Melting Point	N/A
	MSDS	N/A	Flash Point	345.6±27.8 °C

Use of Vaccarin

Vaccarin is an active flavonoid glycoside associated with various biological functions. Vaccarin significantly promote wound healing and endothelial cells and fibroblasts proliferation in the wound site. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway[1][2].

Name	(1S)-1,5-Anhydro-2-O-α-L-arabinopyranosyl-1-{2-[4-(β-D-glucopyran osyloxy)phenyl]-5,7-dihydroxy-4-oxo-4H-chromen-6-yl}-D-glucitol
Synonym	More Synonyms

Description	Vaccarin is an active flavonoid glycoside associated with various biological functions. Vaccarin significantly promote wound healing and endothelial cells and fibroblasts proliferation in the wound site. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Metabolic Disease
References	[1]. Lei Y, et al. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway. Eur J Pharmacol. 2019 May 15;851:13-24. [2]. Hou B,et al. Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo. Acta Cir Bras. 2020 Feb 7;34(12):e201901202.

Description

Related Catalog

Signaling Pathways >> Epigenetics >> AMPK

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

Research Areas >> Metabolic Disease

References

[1]. Lei Y, et al. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway. Eur J Pharmacol. 2019 May 15;851:13-24.

[2]. Hou B,et al. Vaccarin hastens wound healing by promoting angiogenesis via activation of MAPK/ERK and PI3K/AKT signaling pathways in vivo. Acta Cir Bras. 2020 Feb 7;34(12):e201901202.

Density	1.8±0.1 g/cm3
Boiling Point	1088.1±65.0 °C at 760 mmHg
Molecular Formula	C₃₂H₃₈O₁₉
Molecular Weight	726.633
Flash Point	345.6±27.8 °C
Exact Mass	726.200745
PSA	319.12000
LogP	-0.74
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.762