dethiobiotin
dethiobiotin structure
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Common Name | dethiobiotin | ||
|---|---|---|---|---|
| CAS Number | 533-48-2 | Molecular Weight | 214.262 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 476.4±18.0 °C at 760 mmHg | |
| Molecular Formula | C10H18N2O3 | Melting Point | 156-158 °C | |
| MSDS | Chinese USA | Flash Point | 241.9±21.2 °C | |
Use of dethiobiotinD-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation[1]. |
| Name | dethiobiotin |
|---|---|
| Synonym | More Synonyms |
| Description | D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation[1]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 476.4±18.0 °C at 760 mmHg |
| Melting Point | 156-158 °C |
| Molecular Formula | C10H18N2O3 |
| Molecular Weight | 214.262 |
| Flash Point | 241.9±21.2 °C |
| Exact Mass | 214.131744 |
| PSA | 78.43000 |
| LogP | 0.31 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.473 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
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dethiobiotin CAS#:533-48-2 |
| Literature: Journal of the American Chemical Society, , vol. 66, p. 1422 |
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dethiobiotin CAS#:533-48-2 |
| Literature: Agricultural and Biological Chemistry, , vol. 49, # 9 p. 2783 - 2786 |
| Precursor 2 | |
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| DownStream 1 | |
CAS#:80750-24-9| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Easily reversible desthiobiotin binding to streptavidin, avidin, and other biotin-binding proteins: uses for protein labeling, detection, and isolation.
Anal. Biochem. 308 , 343-357, (2002) The high-affinity binding of biotin to avidin, streptavidin, and related proteins has been exploited for decades. However, a disadvantage of the biotin/biotin-binding protein interaction is that it is... |
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Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation.
Proc. Natl. Acad. Sci. U. S. A. 108(49) , 19581-19586, (2011) The process of lipid droplet (LD) formation is an evolutionarily conserved process among all eukaryotes and plays an important role in both cellular physiology and disease. Recently, fat storage-induc... |
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Mutagenesis of a flexible loop in streptavidin leads to higher affinity for the Strep-tag II peptide and improved performance in recombinant protein purification.
Protein Eng. 10(8) , 975-982, (1997) The Strep-tag, an artificial peptide ligand of streptavidin, has gained use as an affinity handle for the purification and detection of recombinant fusion proteins. In an attempt to achieve tighter co... |
| DL-DESTHIOBIOTIN |
| 6-[(4R,5S)-5-Methyl-2-oxo-4-imidazolidinyl]hexanoic acid |
| 6-(5-methyl-2-oxo-imidazolidin-4-yl)hexanoic acid |
| 4-Imidazolidinehexanoic acid, 5-methyl-2-oxo-, (4R,5S)- |
| (4R-cis)-5-methyl-2-oxoimidazolidine-4-hexanoic acid |
| Desthiobiotin |
| 1H-Imidazole-5-hexanoic acid, 4,5-dihydro-2-hydroxy-4-methyl-, (4S,5R)- |
| dethiobiotin |
| d-Desthiobiotin |
| 5-METHYL-2-OXO-4-IMIDAZOLINE-CAPROIC ACID |
| [4R,5S,(+)]-5-Methyl-2-oxo-4-imidazolidinehexanoic acid |
| 5-Methyl-2-oxo-4-imidazolidinehexanoic acid |
| D(-)-desthiobiotin |
| (4R,5S)-dethiobiotin |
| 6-[(4R,5S)-5-Methyl-2-oxoimidazolidin-4-yl]hexanoic acid |