DiOC5(3)

Modify Date: 2024-01-08 19:52:45

DiOC5(3) Structure
DiOC5(3) structure
Common Name DiOC5(3)
CAS Number 53213-81-3 Molecular Weight 544.46800
Density N/A Boiling Point N/A
Molecular Formula C27H33IN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DiOC5(3)


DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical[1][2].

 Names

Name 3,3'-Dipentyloxacarbocyanine iodide,DiOC5(3)
Synonym More Synonyms

 DiOC5(3) Biological Activity

Description DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical[1][2].
Related Catalog
References

[1]. Zhang B, et al. In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3). Biomaterials. 2015;52:14-25.

[2]. Crissman HA, et al. Supravital cell staining with Hoechst 33342 and DiOC5(3). Methods Cell Biol. 1990;33:89-95.

 Chemical & Physical Properties

Molecular Formula C27H33IN2O2
Molecular Weight 544.46800
Exact Mass 544.15900
PSA 35.09000
LogP 3.42740
InChIKey CDLMLYASVIQVPH-UHFFFAOYSA-M
SMILES CCCCCN1C(=CC=Cc2oc3ccccc3[n+]2CCCCC)Oc2ccccc21.[I-]

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM5285250
CHEMICAL NAME :
Benzoxazolium, 3-pentyl-2-((3-pentyl-2(3H)-benzoxazolylidene)-1-prop enyl)-, iodide
CAS REGISTRY NUMBER :
53213-81-3
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H33-N2-O2.I
MOLECULAR WEIGHT :
544.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
5 mg/L
REFERENCE :
IJHYEQ International Journal of Hyperthermia. (Taylor & Francis, 1900 Frost Rd., Suite 101, Bristol, PA 19007) V.1- 1985- Volume(issue)/page/year: 7,243,1991

 Safety Information

Hazard Codes T
Risk Phrases R61;R36/37/38
Safety Phrases S22-S53-S36/37/39-S45

 Synonyms

3,3'-DIPENTYLOXACARBOCYANINE IODIDE,FOR FLUORESCENCE
DiOC5(3) [3,3'-Dipentyloxacarbocyanine iodide]
3,3'-DIPENTYLOXACARBOCYANINE
MFCD00274416
3,3'-DIPENTYLOXACARBOCYANINE IODIDE
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