DiOC5(3)

Names

[ Name ]:
DiOC5(3)

[Synonym ]:
3,3'-DIPENTYLOXACARBOCYANINE IODIDE,FOR FLUORESCENCE
DiOC5(3) [3,3'-Dipentyloxacarbocyanine iodide]
3,3'-DIPENTYLOXACARBOCYANINE
MFCD00274416
3,3'-DIPENTYLOXACARBOCYANINE IODIDE

Biological Activity

[Description]:

DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Zhang B, et al. In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3). Biomaterials. 2015;52:14-25.

[2]. Crissman HA, et al. Supravital cell staining with Hoechst 33342 and DiOC5(3). Methods Cell Biol. 1990;33:89-95.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₃IN₂O₂

[ Molecular Weight ]:
544.46800

[ Exact Mass ]:
544.15900

[ PSA ]:
35.09000

[ LogP ]:
3.42740

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DM5285250

CHEMICAL NAME :: Benzoxazolium, 3-pentyl-2-((3-pentyl-2(3H)-benzoxazolylidene)-1-prop enyl)-, iodide

CAS REGISTRY NUMBER :: 53213-81-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C27-H33-N2-O2.I

MOLECULAR WEIGHT :: 544.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 5 mg/L

REFERENCE :: IJHYEQ International Journal of Hyperthermia. (Taylor & Francis, 1900 Frost Rd., Suite 101, Bristol, PA 19007) V.1- 1985- Volume(issue)/page/year: 7,243,1991

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R61;R36/37/38

[ Safety Phrases ]:
S22-S53-S36/37/39-S45

Related Compounds

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