pyridoxamine phosphate
Modify Date: 2024-01-03 22:08:41
pyridoxamine phosphate structure
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Common Name | pyridoxamine phosphate | ||
|---|---|---|---|---|
| CAS Number | 529-96-4 | Molecular Weight | 248.17300 | |
| Density | 1.559g/cm3 | Boiling Point | 607.3ºC at 760 mmHg | |
| Molecular Formula | C8H13N2O5P | Melting Point | N/A | |
| MSDS | USA | Flash Point | 321.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of pyridoxamine phosphatePyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate[1]. |
| Name | pyridoxamine 5'-phosphate |
|---|---|
| Synonym | More Synonyms |
| Description | Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate[1]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | Pyridoxamine 5′-phosphate can be transformed from pyridoxal 5′-phosphate. Purified His-tagged omega-TA CV2025 from Chromobacterium violaceum is capable of complete conversion of pyridoxal 5′-phosphate to pyridoxamine 5′-phosphate in the presence of (S)-α-methylbenzylamine (MBA) as the amine donor. |
| References |
| Density | 1.559g/cm3 |
|---|---|
| Boiling Point | 607.3ºC at 760 mmHg |
| Molecular Formula | C8H13N2O5P |
| Molecular Weight | 248.17300 |
| Flash Point | 321.1ºC |
| Exact Mass | 248.05600 |
| PSA | 135.71000 |
| LogP | 0.86390 |
| Index of Refraction | 1.622 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| RTECS | UT4710000 |
| HS Code | 2933399090 |
| Precursor 9 | |
|---|---|
| DownStream 2 | |
CAS#:524-36-7
CAS#:54-47-7
CAS#:20905-66-2
CAS#:58-56-0
CAS#:75-04-7
CAS#:302-72-7
CAS#:56-86-0
CAS#:7758-99-8
CAS#:32653-39-7
CAS#:954-27-8| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Fungal recognition enhances mannose receptor shedding through dectin-1 engagement.
J. Biol. Chem. 286(10) , 7822-9, (2011) The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a me... |
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The intestine plays a substantial role in human vitamin B6 metabolism: a Caco-2 cell model.
PLoS ONE 8(1) , e54113, (2013) Vitamin B6 is present in various forms (vitamers) in the diet that need to be metabolized to pyridoxal phosphate (PLP), the active cofactor form of vitamin B6. In literature, the liver has been report... |
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Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.
Neurochem. Int. 59 , 518-524, (2011) Branched-chain amino acids (BCAAs) catabolism follows sequential reactions and their metabolites intersect with other metabolic pathways. The initial enzymes in BCAA metabolism, the mitochondrial bran... |
| Pyridoxamine,3-(dihydrogen phosphate) |
| [4-(aminomethyl)-5-hydroxy-6-methylpyridin-3-yl]methyl dihydrogen phosphate |
| pyrodoxylamine-5'-phosphate |
| Pyridoxamine phosphate [JAN] |
| pyridoxamine phosphate |
| Pyridoxamine-P |
| 4-Aminomethyl-5-hydroxy-6-methyl-3-pyridylmethyl phosphate |
| Pyridoxamine,dihydrogen phosphate |