Cholic acid-13C

Modify Date: 2024-01-02 22:56:45

Cholic acid-13C Structure
Cholic acid-13C structure
Common Name Cholic acid-13C
CAS Number 52886-36-9 Molecular Weight 409.564
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C24H40O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Cholic acid-13C


Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

 Names

Name cholic acid-24-13c
Synonym More Synonyms

 Cholic acid-13C Biological Activity

Description Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Li Y, et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684.

[3]. Pan X, et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C24H40O5
Molecular Weight 409.564
Exact Mass 409.290924
PSA 97.99000
LogP 3.44870
Index of Refraction 1.558

 Synonyms

<24-13C>-Cholsaeure
<24-13C>-Chenodeoxycholsaeure
(3α,5β,7α,12β)-3,7,12-Trihydroxy(24-C)cholan-24-oic acid
Cholan-24-oic-24-C acid, 3,7,12-trihydroxy-, (3α,5β,7α,12β)-
Cholan-24-oic-24-C acid, 3,7,12-trihydroxy-, (3α,5β,7α,12α)-
(3α,5β,7α,12α)-3,7,12-Trihydroxy(24-C)cholan-24-oic acid