SCH 486757

Modify Date: 2025-08-25 18:07:14

SCH 486757 Structure
SCH 486757 structure
Common Name SCH 486757
CAS Number 524019-25-8 Molecular Weight 440.36500
Density N/A Boiling Point N/A
Molecular Formula C24H23Cl2N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SCH 486757


A novel potent, selective, orally active nociceptin/orphanin FQ peptide (NOP, ORL1) receptor agonist with Ki of 4.6 nM, with high selectiivity over classical opioid receptors.

 Names

Name (1R,5S)-8-[bis(2-chlorophenyl)methyl]-3-pyrimidin-2-yl-8-azabicyclo[3.2.1]octan-3-ol
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C24H23Cl2N3O
Molecular Weight 440.36500
Exact Mass 439.12200
PSA 49.25000
LogP 5.32530

 Synonyms

unii-2hv668n62t
SCH 486757
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