9-pentofuranosyl-9H-purin-6-amine

Modify Date: 2024-01-12 15:30:57

9-pentofuranosyl-9H-purin-6-amine structure	Common Name	9-pentofuranosyl-9H-purin-6-amine
	CAS Number	524-69-6	Molecular Weight	267.24
	Density	2.08g/cm3	Boiling Point	676.3ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₃N₅O₄	Melting Point	257.0-257.5ºC (0.4 H2O)
	MSDS	N/A	Flash Point	362.8ºC

Use of 9-pentofuranosyl-9H-purin-6-amine

9-(β-D-Xylofuranosyl)adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name	9-β-D-xylofuranosyladenine
Synonym	More Synonyms

Description	9-(β-D-Xylofuranosyl)adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Density	2.08g/cm3
Boiling Point	676.3ºC at 760 mmHg
Melting Point	257.0-257.5ºC (0.4 H2O)
Molecular Formula	C₁₀H₁₃N₅O₄
Molecular Weight	267.24
Flash Point	362.8ºC
Exact Mass	267.09700
PSA	139.54000
Index of Refraction	1.907