9-pentofuranosyl-9H-purin-6-amine

Names

[ CAS No. ]:
524-69-6

[ Name ]:
9-pentofuranosyl-9H-purin-6-amine

[Synonym ]:
Adenine xyloside
Xylosyl a
Xylosyladenine
9-.β.-D-Xylofuranosyladenine
9-beta-D-xylofuranosyladenine

Biological Activity

[Description]:

9-(β-D-Xylofuranosyl)adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Density]:
2.08g/cm3

[ Boiling Point ]:
676.3ºC at 760 mmHg

[ Melting Point ]:
257.0-257.5ºC (0.4 H2O)

[ Molecular Formula ]:
C₁₀H₁₃N₅O₄

[ Molecular Weight ]:
267.24

[ Flash Point ]:
362.8ºC

[ Exact Mass ]:
267.09700

[ PSA ]:
139.54000

[ Index of Refraction ]:
1.907

Precursor & DownStream

Precursor

DownStream

Related Compounds

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