1,2-NAPHTHOQUINONE

Modify Date: 2024-01-08 20:36:21

1,2-NAPHTHOQUINONE Structure
1,2-NAPHTHOQUINONE structure
Common Name 1,2-NAPHTHOQUINONE
CAS Number 524-42-5 Molecular Weight 158.15300
Density 1.29g/cm3 Boiling Point N/A
Molecular Formula C10H6O2 Melting Point 139-142 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 117.4ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1,2-Naphthoquinone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.29g/cm3
Melting Point 139-142 °C (dec.)(lit.)
Molecular Formula C10H6O2
Molecular Weight 158.15300
Flash Point 117.4ºC
Exact Mass 158.03700
PSA 34.14000
LogP 1.46520
Index of Refraction 1.617
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL7000000
CHEMICAL NAME :
1,2-Naphthoquinone
CAS REGISTRY NUMBER :
524-42-5
BEILSTEIN REFERENCE NO. :
0606546
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H6-O2
MOLECULAR WEIGHT :
158.16
WISWESSER LINE NOTATION :
L66 BVVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,39,1953
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1070 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn,Xi,C,F
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QL7000000
HS Code 2914690090

 Synthetic Route

 Customs

HS Code 2914690090
Summary 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles36

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A new method and tool for detection and quantification of PM oxidative potential.

Environ. Sci. Pollut. Res. Int. 22 , 12469-78, (2015)

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Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

J. Med. Chem. 51 , 1706-18, (2008)

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 Synonyms

EINECS 208-360-2
1,2-Naphthalenedione
MFCD00001698
1,2-NAPHTHOQUINONE
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