1,2-NAPHTHOQUINONE
1,2-NAPHTHOQUINONE structure
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Common Name | 1,2-NAPHTHOQUINONE | ||
|---|---|---|---|---|
| CAS Number | 524-42-5 | Molecular Weight | 158.15300 | |
| Density | 1.29g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H6O2 | Melting Point | 139-142 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 117.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1,2-Naphthoquinone |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.29g/cm3 |
|---|---|
| Melting Point | 139-142 °C (dec.)(lit.) |
| Molecular Formula | C10H6O2 |
| Molecular Weight | 158.15300 |
| Flash Point | 117.4ºC |
| Exact Mass | 158.03700 |
| PSA | 34.14000 |
| LogP | 1.46520 |
| Index of Refraction | 1.617 |
| InChIKey | KETQAJRQOHHATG-UHFFFAOYSA-N |
| SMILES | O=C1C=Cc2ccccc2C1=O |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn,Xi,C,F |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | QL7000000 |
| HS Code | 2914690090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 8 | |
CAS#:574-00-5
CAS#:90-15-3
CAS#:1888-41-1
CAS#:2834-92-6
CAS#:135-19-3
CAS#:529-34-0![[(hydroxy-2' naphthyl)-1]-3 methylene-2 propionate d'ethyle Structure](https://image.chemsrc.com/caspic/482/122628-14-2.png)
CAS#:122628-14-2
CAS#:91-20-3
CAS#:573-97-7
CAS#:708-06-5
CAS#:480-90-0
CAS#:607-24-9
CAS#:56-55-3
CAS#:18398-37-3
CAS#:18099-99-5
CAS#:83-72-7
CAS#:491-31-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2914690090 |
|---|---|
| Summary | 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009) Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligome... |
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A new method and tool for detection and quantification of PM oxidative potential.
Environ. Sci. Pollut. Res. Int. 22 , 12469-78, (2015) Airborne particulate matter (PM) contains several quinones, which are able to generate reactive oxygen species impacting on cell viability. A method able to detect and quantify PM oxidative potential,... |
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Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.
J. Med. Chem. 51 , 1706-18, (2008) Indoleamine 2,3-dioxygenase (IDO) is emerging as an important new therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune supp... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: HTS to identify compounds that promote myeloid differentiation with Validation compou...
Source: NMMLSC
External Id: UNMCMD_HOXA9_MYELOIDDIFFERENTIATION_PRIMARY_VALIDATIONSET
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Inhibition of synthetic amyloid beta42 oligomer formation by Western blot
Source: ChEMBL
Target: N/A
External Id: CHEMBL936122
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Name: Toxicity against Trichoplusia ni (cabbage looper) third-instar larvae stage assessed ...
Source: ChEMBL
Target: Trichoplusia ni
External Id: CHEMBL3049943
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Name: Inhibition of synthetic amyloid beta-42 fibrillation by ThT fluorescence analysis rel...
Source: ChEMBL
Target: N/A
External Id: CHEMBL936124
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Name: Antifeedant activity against Trichoplusia ni (cabbage looper) third-instar larvae sta...
Source: ChEMBL
Target: Trichoplusia ni
External Id: CHEMBL3049944
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Name: Inhibition of human intestinal carboxylesterase
Source: ChEMBL
Target: N/A
External Id: CHEMBL900097
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Name: Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Bas...
Source: Broad Institute
Target: N/A
External Id: 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2
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Name: Inhibition of synthetic amyloid beta-42 fibrillation by light scattering analysis rel...
Source: ChEMBL
Target: N/A
External Id: CHEMBL936125
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| EINECS 208-360-2 |
| 1,2-Naphthalenedione |
| MFCD00001698 |
| 1,2-NAPHTHOQUINONE |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of 1,2-Naphthoquinone? |
| A: LogP of 1,2-Naphthoquinone is 1.46520. |
| Q: What are the upstream materials of 1,2-Naphthoquinone? |
| A: Related upstream materials(CAS) of 1,2-Naphthoquinone: 574-00-5;90-15-3;1888-41-1;2834-92-6;135-19-3;529-34-0;122628-14-2;91-20-3;573-97-7;708-06-5. |
| Q: What are the storage conditions for 1,2-Naphthoquinone? |
| A: Storage conditions for 1,2-Naphthoquinone: 2-8°C. |
| Q: What is the safety information for 1,2-Naphthoquinone? |
| A: Safety information for 1,2-Naphthoquinone: S26-S36. |
| Q: What is the CAS number of 1,2-Naphthoquinone? |
| A: CAS number of 1,2-Naphthoquinone is 524-42-5. |
| Q: What are the downstream products of 1,2-Naphthoquinone? |
| A: Related downstream products(CAS) of 1,2-Naphthoquinone: 480-90-0;607-24-9;56-55-3;18398-37-3;18099-99-5;83-72-7;574-00-5;491-31-6. |
| Q: What is the InChIKey of 1,2-Naphthoquinone? |
| A: InChIKey of 1,2-Naphthoquinone is KETQAJRQOHHATG-UHFFFAOYSA-N. |
| Q: What is the melting point of 1,2-Naphthoquinone? |
| A: Melting point of 1,2-Naphthoquinone is 139-142 °C (dec.)(lit.). |
| Q: What is the molecular formula of 1,2-Naphthoquinone? |
| A: Molecular formula of 1,2-Naphthoquinone is C10H6O2. |
| Q: What English synonyms does 1,2-Naphthoquinone have? |
| A: English synonyms of 1,2-Naphthoquinone: EINECS 208-360-2, 1,2-Naphthalenedione, MFCD00001698, 1,2-NAPHTHOQUINONE. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |