Pipemidic acid

Modify Date: 2024-01-02 02:03:45

Pipemidic acid structure	Common Name	Pipemidic acid
	CAS Number	51940-44-4	Molecular Weight	303.316
	Density	1.4±0.1 g/cm3	Boiling Point	534.9±60.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₇N₅O₃	Melting Point	251-255℃
	MSDS	Chinese USA	Flash Point	277.3±32.9 °C
	Symbol	GHS08	Signal Word	Danger

Use of Pipemidic acid

Pipemidic scid is a new antibacterial agent, is active against Pseudomonas aeruginosa.

Name	pipemidic acid
Synonym	More Synonyms

Description	Pipemidic scid is a new antibacterial agent, is active against Pseudomonas aeruginosa.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection

Density	1.4±0.1 g/cm3
Boiling Point	534.9±60.0 °C at 760 mmHg
Melting Point	251-255℃
Molecular Formula	C₁₄H₁₇N₅O₃
Molecular Weight	303.316
Flash Point	277.3±32.9 °C
Exact Mass	303.133148
PSA	100.35000
LogP	-0.16
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.617

Pipemidic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV1153800

CHEMICAL NAME :: Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 5,8-dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)-

CAS REGISTRY NUMBER :: 51940-44-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C14-H17-N5-O3

MOLECULAR WEIGHT :: 303.36

WISWESSER LINE NOTATION :: T66 BN DN GV JNJ HVQ J2 C- DT6M DNTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1438 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 529 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1213 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 90 gm/kg/30D-I

TOXIC EFFECTS :: Cardiac - changes in heart weight Liver - changes in liver weight Endocrine - changes in thymus weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9100 mg/kg/26W-I

TOXIC EFFECTS :: Gastrointestinal - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 22400 mg/kg

SEX/DURATION :: female 8-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - live birth index (measured after birth)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1400 mg/kg

SEX/DURATION :: female 8-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 22400 mg/kg

SEX/DURATION :: female 15-22 day(s) after conception lactating female 20 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 152 mg/kg

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,397,1988

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H317-H334
Precautionary Statements	P261-P280-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi
Risk Phrases	42/43
Safety Phrases	22-36/37-45
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	UV1153800

N/A

CAS#:51940-43-3

Pipemidic acid

CAS#:51940-44-4

Literature: Dainippon Pharmaceutical Co., Ltd. Patent: US3962443 A1, 1976 ;

N/A

CAS#:52070-73-2

Pipemidic acid

CAS#:51940-44-4

Literature: Dainippon Pharmaceutical Co., Ltd. Patent: US3962443 A1, 1976 ;

Piperazine Hexa...

CAS#:142-63-2

2-Methylmercapt...

CAS#:19572-11-3

Pipemidic acid

CAS#:51940-44-4

Literature: Dainippon Pharmaceutical Co., Ltd. Patent: US3962443 A1, 1976 ;

Diethyl sulfate

CAS#:64-67-5

pipemidic acid

CAS#:52070-56-1

Pipemidic acid

CAS#:51940-44-4

N/A

CAS#:51940-55-7

Literature: Dainippon Pharmaceutical Co., Ltd. Patent: US3962443 A1, 1976 ;

Precursor 3
CAS#:142-63-2 Piperazine Hexa... CAS#:19572-11-3 2-Methylmercapt... CAS#:64-67-5 Diethyl sulfate
DownStream 0

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Piperamic Acid

Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-

EINECS 257-530-2

Pipemidic acid

Pyrido(2,3-d)pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)-

8-ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid

8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid

MFCD00057291

8-Ethyl-5-oxo-2-(1-piperazinyl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid

8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic Acid

8-ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid

8-ethyl-5-oxo-2-piperazin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pipemidic acid
Price: ￥898.0/10g ￥3158.0/50g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pipemidic acid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pipemidic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Pipemidic acid
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Pipemidic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: $66/10mM*1mLinDMSO

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Pipemidic acid

Use of Pipemidic acid

Names

Pipemidic acid Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

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