Diethyl sulfate

Modify Date: 2025-08-21 17:18:22

Diethyl sulfate structure	Common Name	Diethyl sulfate
	CAS Number	64-67-5	Molecular Weight	154.185
	Density	1.2±0.1 g/cm3	Boiling Point	208.0±0.0 °C at 760 mmHg
	Molecular Formula	C₄H₁₀O₄S	Melting Point	-24 °C
	MSDS	Chinese USA	Flash Point	78.3±0.0 °C
	Symbol	GHS05, GHS06, GHS08	Signal Word	Danger

Name	Diethyl sulfate
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	208.0±0.0 °C at 760 mmHg
Melting Point	-24 °C
Molecular Formula	C₄H₁₀O₄S
Molecular Weight	154.185
Flash Point	78.3±0.0 °C
Exact Mass	154.029984
PSA	60.98000
LogP	1.14
Vapour density	5.3 (vs air)
Vapour Pressure	0.3±0.3 mmHg at 25°C
Index of Refraction	1.426
Stability	Moisture sensitive. May react violently with oxidizing agents.
Water Solubility	5 g/L (20 ºC)

Diethyl sulfate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WS7875000

CHEMICAL NAME :: Sulfuric acid, diethyl ester

CAS REGISTRY NUMBER :: 64-67-5

LAST UPDATED :: 199806

DATA ITEMS CITED :: 84

MOLECULAR FORMULA :: C4-H10-O4-S

MOLECULAR WEIGHT :: 154.20

WISWESSER LINE NOTATION :: 2OSWO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 880 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 647 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 600 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3700 mg/kg/81W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/kg/32W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 85 mg/kg female 15 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 340 mg/kg

SEX/DURATION :: female 15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Heritable translocation test

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Dominant lethal test

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: DNA damage

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: DNA inhibition

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Dominant lethal test

TYPE OF TEST :: Dominant lethal test

TYPE OF TEST :: Dominant lethal test

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 100 mmol/L

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 80,496,1961 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,277,1974 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,213,1992 IARC Cancer Review:Human Limited Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,198,1987 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,213,1992 IARC Cancer Review:Group 2A IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,213,1992 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993 OEL-SWITZERLAND:TWA 0.03 ppm (0.2 mg/m3);Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84284 No. of Facilities: 116 (estimated) No. of Industries: 4 No. of Occupations: 11 No. of Employees: 1646 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84284 No. of Facilities: 86 (estimated) No. of Industries: 4 No. of Occupations: 3 No. of Employees: 2260 (estimated) No. of Female Employees: 165 (estimated)

Symbol	GHS05, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H302 + H332-H311-H314-H340-H350
Precautionary Statements	P201-P260-P280-P303 + P361 + P353-P305 + P351 + P338-P308 + P313
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R20/21/22;R34;R45;R46
Safety Phrases	S53-S45
RIDADR	UN 1594 6.1/PG 2
WGK Germany	3
RTECS	WS7875000
Packaging Group	II
Hazard Class	6.1
HS Code	2920909090

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HS Code	2920909090
Summary	2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB.

Mol. Microbiol. 70 , 323-40, (2008)

Contact-dependent growth inhibition (CDI) is a phenomenon by which bacterial cell growth is regulated by direct cell-to-cell contact via the CdiA/CdiB two-partner secretion system. Characterization of...

Genetic effects of dimethyl sulfate, diethyl sulfate, and related compounds.

Mutat. Res. 75(1) , 63-129, (1980)

DMS and DES are monofunctional alkylating agents that have been shown to induce mutations, chromosomal aberrations, and other genetic alterations in a diversity of organisms. They have also been shown...

Measurement of ethyl glucuronide, ethyl sulphate and their ratio in the urine and serum of healthy volunteers after two doses of alcohol.

Alcohol Alcohol. 48(1) , 74-82, (2013)

Ethyl glucuronide (EtG) and ethyl sulphate (EtS) are minor metabolites of ethanol, and their presence in urine provides a strong indication of recent alcohol administration. In this study, we performe...

Diethyl sulfate

EINECS 200-589-6

Ethylsulpate

MFCD00009099

Diaethylsulfat

sulfatediethylique

DIETHYL MONOSULFATE

Sulfuric acid, diethyl ester

Diethylsulfate

DIETHYL SULPHATE

ETHYL SULFATE

Diethylsulfat

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Diethyl sulfate
Price: Check
Purity: 99.0%
Delivery: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Diethyl sulfate
Price: ￥88.0/500ml
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Diethyl sulfate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Diethyl sulfate

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CHEMICAL IDENTIFICATION

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MUTATION DATA

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