3-Methylbutanoic acid

Modify Date: 2025-08-24 19:09:02

3-Methylbutanoic acid structure	Common Name	3-Methylbutanoic acid
	CAS Number	503-74-2	Molecular Weight	102.132
	Density	1.0±0.1 g/cm3	Boiling Point	175.3±8.0 °C at 760 mmHg
	Molecular Formula	C₅H₁₀O₂	Melting Point	-35 °C
	MSDS	Chinese USA	Flash Point	70.6±0.0 °C
	Symbol	GHS05	Signal Word	Danger

Use of 3-Methylbutanoic acid

3-Methylbutanoic acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.

Name	isovaleric acid
Synonym	More Synonyms

Description	3-Methylbutanoic acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. Ackman RG, et al. Birthweights in the Faroe Islands: possible role of isovaleric acid. J Intern Med. 1989 Feb;225(2):73-5.

Density	1.0±0.1 g/cm3
Boiling Point	175.3±8.0 °C at 760 mmHg
Melting Point	-35 °C
Molecular Formula	C₅H₁₀O₂
Molecular Weight	102.132
Flash Point	70.6±0.0 °C
Exact Mass	102.068077
PSA	37.30000
LogP	1.13
Vapour Pressure	0.6±0.7 mmHg at 25°C
Index of Refraction	1.418
Water Solubility	25 g/L (20 ºC)

3-Methylbutanoic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NY1400000

CHEMICAL NAME :: Isovaleric acid

CAS REGISTRY NUMBER :: 503-74-2

BEILSTEIN REFERENCE NO. :: 1098522

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C5-H10-O2

MOLECULAR WEIGHT :: 102.15

WISWESSER LINE NOTATION :: QV1Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/31/1972

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,841,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/31/1972 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/31/1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1120 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 18,141,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 310 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/31/1972 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84451 No. of Facilities: 35 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 69 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84451 No. of Facilities: 148 (estimated) No. of Industries: 4 No. of Occupations: 16 No. of Employees: 6695 (estimated) No. of Female Employees: 1037 (estimated)

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive;T:Toxic;
Risk Phrases	R22;R24;R34
Safety Phrases	S26-S36/37/39-S45-S38-S28A
RIDADR	UN 3265 8/PG 2
WGK Germany	1
RTECS	NY1400000
Packaging Group	III
Hazard Class	6.1
HS Code	2915600000

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HS Code	2915900090
Summary	2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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Butanoic acid, 3-methyl-

1,1-DIMETHYLPROPYL 3-METHYLBUTANOATE

Butanoic acid,3-methyl-,1,1-dimethylpropyl ester

Isovaleric acid

MFCD00002726

isobutanoic acid

3-Methylbutanoic acid

iso-valeric acid

3-Methyl-n-butyric acid

tert-Amyl isovalerate

β-methylbutyric acid

3-methyl butyric acid

2-Isovalerylamino-naphthalin

Isovaleriansaeure-tert-pentylester

3-Methylbutyric Acid

EINECS 207-975-3

QV1Y1&1

tert-Pentyl alcohol,isovalerate

3-Methylbutanoic acid,3-Methylbutyric acid

3-methyl-butanoic acid,1,1-dimethylpropyl ester

i-butanoic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3-Methylbutanoic acid
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 3-Methylbutanoic acid
Price: ￥78.0/100ml ￥218.0/500ml
Purity: 99.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Isovaleric acid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isovaleric acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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3-Methylbutanoic acid suppliers

Price: ￥550/10 mM * 1 mL in DMSO

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3-Methylbutanoic acid

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