TIE-2/VEGFR-2 kinase-IN-2

Modify Date: 2025-08-27 15:45:16

TIE-2/VEGFR-2 kinase-IN-2 Structure
TIE-2/VEGFR-2 kinase-IN-2 structure
 Common Name TIE-2/VEGFR-2 kinase-IN-2
CAS Number 501693-48-7 Molecular Weight 431.34
Density N/A Boiling Point N/A
Molecular Formula C20H13F4N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TIE-2/VEGFR-2 kinase-IN-2


TIE-2/VEGFR-2 kinase-IN-2 is a potent dual VEGFR2 and Tie-2 inhibitor with pIC50 values of 8.61 and 8.56, respectively[1]. TIE-2/VEGFR-2 kinase-IN-2 is an anti-angiogenic agent and can be used for cancer research[2].

 Names

Name TIE-2/VEGFR-2 kinase-IN-2

 TIE-2/VEGFR-2 kinase-IN-2 Biological Activity

Description TIE-2/VEGFR-2 kinase-IN-2 is a potent dual VEGFR2 and Tie-2 inhibitor with pIC50 values of 8.61 and 8.56, respectively[1]. TIE-2/VEGFR-2 kinase-IN-2 is an anti-angiogenic agent and can be used for cancer research[2].
Related Catalog
Target

VEGFR-2

Tie-2

References

[1]. Yasushi Miyazaki, et al. Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1773-8.

 Chemical & Physical Properties

Molecular Formula C20H13F4N5O2
Molecular Weight 431.34
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Chemsrc provides TIE-2/VEGFR-2 kinase-IN-2(CAS#:501693-48-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TIE-2/VEGFR-2 kinase-IN-2 are included as well.>> amp version: TIE-2/VEGFR-2 kinase-IN-2

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